Browsing by Author "Weir, Scott J."
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Preclinical pharmacokinetics of fosciclopirox, a novel treatment of urothelial cancers, in rats and dogs
Weir, Scott J.; Wood, Robyn; Schorno, Karl; Brinker, Amanda E.; Ramamoorthy, Prabhu; Heppert, Kathy; Taylor, John A., III; Tanol, Mehmet (Amer Soc Pharmacology Experimental Therapeutics, 2019)Pharmacokinetic studies in rats and dogs were performed to characterize the in vivo performance of a novel prodrug, fosciclopirox. Ciclopirox olamine (CPX-O) is a marketed topical antifungal agent with demonstrated in vitro ...