Browsing by Author "Fışgın, Tunç"
Now showing items 1-20 of 24
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Are the anxiety levels of pediatric hematology-oncology patients different from healthy peers during the COVID-19 outbreak?
Çakıroğlu, Süleyman; Yeltekin, Ceren; Fışgın, Tunç; Öner, Özlem B.; Aksoy, Başak A.; Bozkurt, Ceyhun (Lippincott Williams and Wilkins, 2020)The COVID-19 outbreak has caused anxiety among children with hematology-oncology disease and their families, as it has in every segment of society. In this study, we aimed to detect the anxiety levels of children with ... -
Biallelic form of a known CD3E mutation in a patient with severe combined immunodeficiency
Erman, Baran; Fırtına, Sinem; Fışgın, Tunç; Bozkurt, Ceyhun; Cipe, Funda Erol (Springer/Plenum Publishers, 2020)To the Editor: T cell receptor (TCR) complex consists of αβ or γδ TCR chains in combination with four CD3 subunits, CD3ε, CD3γ, CD3δ, and CDζ [1]. This complex is required for thymocyte development and the initiation of T ... -
Busulfan–fudarabine‑ or treosulfan–fudarabine‑based myeloablative conditioning for children with thalassemia major
Lüftinger, Roswitha; Zubarovskaya, Natalia; Galimard, Jacques‑Emmanuel; Cseh, Annamaria; Salzer, Elisabeth; Locatelli, Franco; Algeri, Mattia; Yeşilipek, Akif; Fuente, Josu de la; Isgro, Antonella; Alseraihy, Amal; Angelucci, Emanuele; Smiers, Frans J.; Nasa, Giorgia La La; Zecca, Marco; Fışgın, Tunç; Ünal, Emel; Kleinschmidt, Katharina; Peters, Christina; Lankester, Arjan; Çorbacıoğlu, Selim (Annals of Hematology, 2021)Signifcant advances in supportive care for patients with transfusion-dependent thalassemia major (TDT) have improved patients’ life expectancy. However, transfusion-associated iron overload remains a signifcant barrier ... -
Central nervous system fungal infections in children with leukemia and undergoing hematopoietic stem cell transplantation: A retrospective multicenter study
Karaman, Serap; Kebudi, Rejin; Kızılocak, Hande; Karakaş, Zeynep; Demirağ, Bengü; Evim, Melike Sezgin; Yaralı, Neşe; Kaya, Zühre; Karagün, Barbaros Şahin; Aydoğdu, Selime; Çalışkan, Ümran; Ayhan, Aylin Canbolat; Bahadır, Ayşenur; Çakır, Betül; Güner, Burçak T.; Albayrak, Canan; Karapınar, Deniz Yılmaz; Kazancı, Elif Güner; Ünal, Ekrem; Türkkan, Emine; Akıcı, Ferhan; Bor, Özcan; Vural, Sema; Yılmaz, Şebnem; Apak, Hilmi; Baytan, Birol; Tahta, Neryal Müminoğlu; Güzelküçük, Zeliha; Koçak, Ülker; Antmen, Bülent; Tokgöz, Hüseyin; Fışgın, Tunç; Özdemir, Nihal; Güneş, Adalet Meral; Vergin, Canan; Ünüvar, Ayşegül; Özbek, Namık; Tuğcu, Deniz; Bay, Sema Büyükkapu; Tanyıldız, Hikmet Gülşah; Celkan, Tiraje (2022)Background: Central nervous system fungal infections (CNSFI) are seen in patients with hematologic malignancies and have high morbidity and mortality. Because of their rarity, there is limited data on CNSFI in children ... -
Comparison of allogeneic stem cell transplantation results from related or unrelated donors in beta-thalassemia major
Aydoğdu, Selime; Mergen, Azize; Aksoy, Başak; Çokluk, Mila N.; Dikme, Gürcan; Cipe, Funda; Bozkurt, Ceyhun (Nature Publishing Group, 2019)Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for beta-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord ... -
Comparison of hematopoietic stem cell transplantation results in patients with beta-thalassemia major from three different graft types
Aydoğdu, Selime; Toret, Ersin; Aksoy, Başak A.; Aydın, Muhammed Fatih; Cipe, Funda E.; Bozkurt, Ceyhun; Fışgın, Tunç (Taylor & Francis Ltd, 2021)Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for beta-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord ... -
Comparison of turkish stem cell coordination center (TURKOK) with Istanbul University bone marrow bank (TRIS); a single center experience in match unrelated donors
Mergen, Azize; Aydoğdu, Selime; Aksoy, Başak; Savcı, Yunus Emre; Dikme, Gürcan; Cipe, Funda; Fışgın, Tunç (Nature Publishing Group, 2019)[No abstract available] -
Could the COVID-19 infection have a better prognosis than expected in pediatric hematology oncology and bone marrow transplant patients?
Öner, Özlem Başoğlu; Aksoy, Barış Adaklı; Sütçü, Murat; Çipe, Funda; Atça, Ali Önder; Bozkurt, Ceyhun; Fışgın, Tunç (Scientific Letter, 2021)Coronavirus disease 2019 (COVID-19) is a pandemic that spread rapidly worldwide (1). So far, very few reports concerning the impact of COVID-19 among patients with pediatric hematologic-oncologic diseases are available ... -
COVID-19 infection in children with cancer and stem cell transplant recipients in Turkey: A nationwide study
Kebudi, Rejin; Kurucu, Nilgün; Tuğcu, Deniz; Hacısalihoğlu, Sadan; Fışgın, Tunç; Ocak, Süheyla; Kara, Ateş; Bozkurt, Ceyhun (Wiley, 2021)Adults with cancer are reported to have a higher risk for coronavirus disease (COVID-19) infection and more severe disease and mortality than the general population.1,2 Although children seem to be at a lower risk for ... -
Donor lymphocyte infusion administrations after allogeneic stem cell transplantations in pediatrics: A single center experience
Aydoğdu, Selime; Mergen, Azize; Aksoy, Başak; Akbay, Hazal S.; Cipe, Funda; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)Allogeneic stem cell transplantation (allo-SCT) is considered the cornerstone in the treatment of several malignant and not malignant hematological diseases. However, relapse of hematological disease after allo-SCT is ... -
The effect of biofilm inhibitor N-acetylcysteine on the minimum inhibitory concentration of antibiotics used in Gram-negative bacteria in the biofilm developed on catheters
The study determined the effect of N-acetylcysteine (NAC) on the susceptibility of various antibiotics used to treat Gram-negative catheter-related infection in isolates obtained from pediatric patients admitted to the ... -
Evaluation of the risk factors for BK virus-associated hemorrhagic cystitis in pediatric bone marrow transplantation patients: Does post-transplantation cyclophosphamide increase the frequency?
Ersoy, Gizem Zengin; Bozkurt, Ceyhun; Aksoy, Başak Adaklı; Öner, Özlem Başoğlu; Aydoğdu, Selime; Çipe, Funda; Sütçü, Murat; Özkaya, Ozan; Fışgın, Tunç (2022)Background: BKV-HC is one of the most significant complications of HSCT. This ret -rospective study aimed to determine the frequency of BKV-HC in pediatric patients undergoing HSCT, detect the ... -
Extracorporeal photopheresis treatment for steroid resistant graft versus host disease in pediatrics: Single center experience
Aksoy, Başak Adaklı; Savcı, Yunus Emre; Mergen, Azize; Aydoğdu, Selime; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)[No abstract available] -
Farklı yaş grubundaki sıçanlarda laparaskopik ve açık cerrahi sonrası hücresel immun yanıt
Öztaş, Tülin; Bıçakçı, Ünal; Rızalar, Rıza; Fışgın, Tunç (2021)GİRİŞ ve AMAÇ: Bu çalışmanın amacı farklı yaş gruplarındaki sıçanlarda açık ve laparoskopik cerrahi sonrası hücresel immun yanıttaki değişiklikleri karşılaştırmaktır. YÖNTEM ve GEREÇLER: Çalışmada 24 adet Wistar ... -
Immune reconstitution of thalassemia major patients after 1 year of hematopoetic stem cell transplantation
Cipe, Funda Erol; Bozkurt, Ceyhun; Aksoy, Başak Adaklı; Aydoğdu, Selime; Dikme, Gürcan; Fışgın, Tunç (Nature Publishing Group, 2019)Immune reconstitution inflammatory syndrome (IRIS) is a clinical condition emerging after immune recovery of an immunocompromised status, mostly in human immunodeficiency virus infected patients but also in several other ... -
Invasive saprochaete capitata infection in a patient with autosomal recessive CARD9 deficiency and a review of the literature
Erman, Baran; Fırtına, Sinem; Aksoy, Başak Adaklı; Aydoğdu, Selime; Genç, Gonca Erköse; Doğan, Öner; Cipe, Funda Erol; Fışgın, Tunç (Springer/Plenum Publishers, 2020)Purpose Autosomal recessive (AR) CARD9 deficiency is an inherited immune disorder which results in impaired innate immunity against various fungi. Superficial and invasive fungal infections, mainly caused by Candida or ... -
Primary immunodeficiencies: HSCT experiences of a single center in Turkey
Cipe, Funda Erol; Aydoğdu, Selime; Dikme, Gürcan; Kıykım, Ayça; Aydoğmuş, Çiğdem; Yücel, Esra; Bozkurt, Ceyhun; Fışgın, Tunç (Pediatric Transplantation, 2021)Background Primary immunodeficiency diseases (PID) are characterized by the occurrence of frequent infections and are caused by many genetic defects. Hematopoietic stem cell transplantation (HSCT) is the only curative ... -
Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia
Hazar, Volkan; Tezcan Karasu, Gülsün; Öztürk, Gülyüz; Küpesiz, Alphan; Aksoylar, Serap; Özbek, Namık; Gökçe, Müge; Fışgın, Tunç (Wiley, 2021)Background Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes are ... -
Stem cell transplantation for high-risk acute lymphoblastic leukemia in a developing country: A single-center experience
Bozkurt, C.; Aksoy, B.; Aydoğdu, S.; Bozkurt, S.; Cipe, F.; Öner, O.; Fışgın, Tunç (Wiley, 2020)[No abstract available] -
Thalassemia-free and graft-versus-host-free survival: outcomes of hematopoietic stem cell transplantation for thalassemia major, Turkish experience
Yeşilipek, M. Akif; Uygun, Vedat; Küpesiz, Alphan; Karasu, Gülsün; Ertem, Mehmet; Şaşmaz, İlgen; Daloğlu, Hayriye; Güler, Elif; Hazar, Volkan; Fışgın, Tunç; Sezgin, Gülay; Kansoy, Savaş; Kuşkonmaz, Barış; Akıncı, Burcu; Özbek, Namık; Ünal İnce, Elif; Öztürkmen, Seda; Tayfun Küpesiz, Funda; Yalçın, Koray; Anak, Sema; Bozkurt, Ceyhun; Karakükçü, Musa; Küpeli, Serhan; Albayrak, Davut; Öniz, Haldun; Aksoylar, Serap; Visal Okur, Fatma; Albayrak, Canan; Demir Yenigürbüz, Fatma; Ok Bozkaya, İkbal; İleri, Talia; Gürsel, Orhan; Karagün, Barboras Şahin; Tüysüz Kintrup, Gülen; Çelen, Suna; Elli, Murat; Adaklı Aksoy, Başak; Yılmaz, Ebru; Tanyeli, Atilla; Turan Akyol, Şule; Önder Siviş, Zuhal; Özek, Gülcihan; Uçkan, Duygu; Kartal, İbrahim; Atay, Didem; Akyay, Arzu; Arman Bilir, Özlem; Çakmaklı, Hasan Fatih; Kürekçi, Emin; Malbora, Barış; Akbayram, Sinan; Demir, Hacı Ahmet; Kılıç, Suar Çakı; Güneş, Adalet Meral; Zengin, Emine; Özmen, Salih; Antmen, Ali Bülent (Springer, 2022)We report the national data on the outcomes of hematopoietic stem cell transplantation (HSCT) for thalassemia major (TM) patients in Turkey on behalf of the Turkish Pediatric Stem Cell Transplantation Group. We retrospectively ...
