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Antibiotic loaded nanocapsules functionalized with aptamer gates for targeted destruction of pathogens
(Royal Soc Chemistry, 2015)
In this study, we designed aptamer-gated nanocapsules for the specific targeting of cargo to bacteria with controlled release of antibiotics based on aptamer-receptor interactions. Aptamer-gates caused a specific decrease ...
NanoKeepers: Stimuli responsive nanocapsules for programmed specific targeting and drug delivery
(Royal Soc Chemistry, 2014)
Bacterial resistance is a high priority clinical issue worldwide. Thus, an effective system that rapidly provides specific treatment for bacterial infections using controlled dose release remains an unmet clinical need. ...
Pathogen detection by core-shell type aptamer-magnetic preconcentration coupled to real-time PCR
(Academic Press Inc Elsevier Science, 2014)
The presence of pathogenic bacteria is a major health risk factor in food samples and the commercial food supply chain is susceptible to bacterial contamination. Thus, rapid and sensitive identification methods are in ...
Aptamers: Molecular tools for medical diagnosis
(Bentham Science Publ Ltd, 2015)
Aptamers have been increasingly applied in biomedical field as a class of biorecognition elements that possess many advantages such as high specificity and binding affinity, easy synthesis, easy modification, small size, ...
Nanocapsules in biomedicine promises and challenges
(Scrivener Publishing Llc, 2015)
With the recent advances in nanotechnology, in the past decade, the ways of doing biomedicine have been reshaped considerably. Nanometer-size structures (nanoparticles, nanowires, nanocapsules, etc.) are used in biosensing, ...
Portable bioactive paper-based sensor for quantification of pesticides
(Hindawi Ltd, 2013)
A paper-based biosensor was developed for the detection of the degradation products of organophosphorus pesticides. The biosensor quantifies acetylcholine esterase inhibitors in a fast, disposable, cheap, and accurate ...
Nanoparticle embedded enzymes for improved lateral flow sensors
(Royal Soc Chemistry, 2013)
In this study, combining the nanoparticle embedded sensors with lateral flow assays, a novel strategy for ensuring the quality of signalling in lateral flow assays (LFAs) was developed. A LFA for reactive oxygen species ...
Aptamers in medical diagnosis
(Pan Stanford Publishing Pte. Ltd., 2016)
Aptamers have been increasingly applied in biomedical field as a class of biorecognition elements that possess many advantages such as high specificity and binding affinity, easy synthesis, easy modification, small size, ...
Label-free lateral flow assay for Listeria monocytogenes by aptamer-gated release of signal molecules
(Academic Press Inc Elsevier Science, 2019)
Lateral flow assay (LFA) type of biosensors have been popular due to cost-effectiveness and easy-interpretation for instant results, most common examples of applications being pregnancy tests, food safety or medical ...