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Unexpected debris after post thawing donor stem cells in autologous transplantation

Aksoy, Başak Adaklı; Fışgın, Tunç (Elsevier Editora Ltda, 2021)

High dose chemotherapy followed by autologous stem cell transplantation is still a salvage therapy for those patients having relapsed Wilms’ tumor. The most common stem cell source is peripheral blood especially after ...

COVID-19 infection in children with cancer and stem cell transplant recipients in Turkey: A nationwide study

Kebudi, Rejin; Kurucu, Nilgün; Tuğcu, Deniz; Hacısalihoğlu, Sadan; Fışgın, Tunç; Ocak, Süheyla; Kara, Ateş; Bozkurt, Ceyhun (Wiley, 2021)

Adults with cancer are reported to have a higher risk for coronavirus disease (COVID-19) infection and more severe disease and mortality than the general population.1,2 Although children seem to be at a lower risk for ...

Comparison of hematopoietic stem cell transplantation results in patients with beta-thalassemia major from three different graft types

Aydoğdu, Selime; Toret, Ersin; Aksoy, Başak A.; Aydın, Muhammed Fatih; Cipe, Funda E.; Bozkurt, Ceyhun; Fışgın, Tunç (Taylor & Francis Ltd, 2021)

Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for beta-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord ...

Busulfan–fudarabine‑ or treosulfan–fudarabine‑based myeloablative conditioning for children with thalassemia major

Lüftinger, Roswitha; Zubarovskaya, Natalia; Galimard, Jacques‑Emmanuel; Cseh, Annamaria; Salzer, Elisabeth; Locatelli, Franco; Algeri, Mattia; Yeşilipek, Akif; Fuente, Josu de la; Isgro, Antonella; Alseraihy, Amal; Angelucci, Emanuele; Smiers, Frans J.; Nasa, Giorgia La La; Zecca, Marco; Fışgın, Tunç; Ünal, Emel; Kleinschmidt, Katharina; Peters, Christina; Lankester, Arjan; Çorbacıoğlu, Selim (Annals of Hematology, 2021)

Signifcant advances in supportive care for patients with transfusion-dependent thalassemia major (TDT) have improved patients’ life expectancy. However, transfusion-associated iron overload remains a signifcant barrier ...

Evaluation of the risk factors for BK virus-associated hemorrhagic cystitis in pediatric bone marrow transplantation patients: Does post-transplantation cyclophosphamide increase the frequency?

Ersoy, Gizem Zengin; Bozkurt, Ceyhun; Aksoy, Başak Adaklı; Öner, Özlem Başoğlu; Aydoğdu, Selime; Çipe, Funda; Sütçü, Murat; Özkaya, Ozan; Fışgın, Tunç (2022)

Background: BKV-HC is one of the most significant complications of HSCT. This ret -rospective study aimed to determine the frequency of BKV-HC in pediatric patients undergoing HSCT, detect the ...

Farklı yaş grubundaki sıçanlarda laparaskopik ve açık cerrahi sonrası hücresel immun yanıt

Öztaş, Tülin; Bıçakçı, Ünal; Rızalar, Rıza; Fışgın, Tunç (2021)

GİRİŞ ve AMAÇ: Bu çalışmanın amacı farklı yaş gruplarındaki sıçanlarda açık ve laparoskopik cerrahi sonrası hücresel immun yanıttaki değişiklikleri karşılaştırmaktır. YÖNTEM ve GEREÇLER: Çalışmada 24 adet Wistar ...

The effect of biofilm inhibitor N-acetylcysteine on the minimum inhibitory concentration of antibiotics used in Gram-negative bacteria in the biofilm developed on catheters

Aksoy, Nilay; Vatansever, Cansu; Ersoy, Gizem Zengin; Aksoy, Başak Adaklı; Fışgın, Tunç (2022)

The study determined the effect of N-acetylcysteine (NAC) on the susceptibility of various antibiotics used to treat Gram-negative catheter-related infection in isolates obtained from pediatric patients admitted to the ...

Central nervous system fungal infections in children with leukemia and undergoing hematopoietic stem cell transplantation: A retrospective multicenter study

Karaman, Serap; Kebudi, Rejin; Kızılocak, Hande; Karakaş, Zeynep; Demirağ, Bengü; Evim, Melike Sezgin; Yaralı, Neşe; Kaya, Zühre; Karagün, Barbaros Şahin; Aydoğdu, Selime; Çalışkan, Ümran; Ayhan, Aylin Canbolat; Bahadır, Ayşenur; Çakır, Betül; Güner, Burçak T.; Albayrak, Canan; Karapınar, Deniz Yılmaz; Kazancı, Elif Güner; Ünal, Ekrem; Türkkan, Emine; Akıcı, Ferhan; Bor, Özcan; Vural, Sema; Yılmaz, Şebnem; Apak, Hilmi; Baytan, Birol; Tahta, Neryal Müminoğlu; Güzelküçük, Zeliha; Koçak, Ülker; Antmen, Bülent; Tokgöz, Hüseyin; Fışgın, Tunç; Özdemir, Nihal; Güneş, Adalet Meral; Vergin, Canan; Ünüvar, Ayşegül; Özbek, Namık; Tuğcu, Deniz; Bay, Sema Büyükkapu; Tanyıldız, Hikmet Gülşah; Celkan, Tiraje (2022)

Background: Central nervous system fungal infections (CNSFI) are seen in patients with hematologic malignancies and have high morbidity and mortality. Because of their rarity, there is limited data on CNSFI in children ...

Thalassemia-free and graft-versus-host-free survival: Outcomes of hematopoietic stem cell transplantation for thalassemia major, Turkish experience

Yeşilipek, M. Akif; Uygun, Vedat; Küpesiz, Alphan; Karasu, Gülsün; Öztürk, Gülyüz; Ertem, Mehmet; Şaşmaz, İlgen; Daloğlu, Hayriye; Güler, Elif; Hazar, Volkan; Fışgın, Tunç; Sezgin, Gülay; Kansoy, Savaş; Kuşkonmaz, Barış; Akıncı, Burcu; Özbek, Namık; Ünal-İnce, Elif; Öztürkmen, Seda; Küpesiz-Tayfun, Funda; Yalçın, Koray; Anak, Sema; Bozkurt, Ceyhun; Karakükçü, Musa; Küpeli, Serhan; Albayrak, Davut; Öniz, Haldun; Aksoylar, Serap; Visal-Okur, Fatma; Albayrak, Canan; Demir-Yenigürbüz, Fatma; Ok-Bozkaya, İkbal; İleri, Talia; Gürsel, Orhan; Karagün, Barbaros Şahin; Tüysüz-Kintrup, Gülen; Çelen, Suna; Elli, Murat; Adaklı-Aksoy, Başak; Yılmaz, Ebru; Tanyeli, Atila; Turan-Akyol, Şule; Önder-Siviş, Zuhal; Özek, Gülcihan; Uçkan, Duygu; Kartal, İbrahim; Atay, Didem; Arzu, Akyay; Arman-Bilir, Özlem; Çakmaklı, Hasan Fatih; Kürekçi, Emin; Malbora, Barış; Akbayram, Sinan; Demir, Hacı Ahmet; Kılıç, Suar Çakı; Güneş, Adalet Meral; Zengin, Emine; Özmen, Salih; Antmen, Ali Bülent (Bone Marrow Transplantation, 2022)

We report the national data on the outcomes of hematopoietic stem cell transplantation (HSCT) for thalassemia major (TM) patients in Turkey on behalf of the Turkish Pediatric Stem Cell Transplantation Group. We retrospectively ...

Primary immunodeficiencies: HSCT experiences of a single center in Turkey

Cipe, Funda Erol; Aydoğdu, Selime; Dikme, Gürcan; Kıykım, Ayça; Aydoğmuş, Çiğdem; Yücel, Esra; Bozkurt, Ceyhun; Fışgın, Tunç (Pediatric Transplantation, 2021)

Background Primary immunodeficiency diseases (PID) are characterized by the occurrence of frequent infections and are caused by many genetic defects. Hematopoietic stem cell transplantation (HSCT) is the only curative ...