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Busulfan–fudarabine‑ or treosulfan–fudarabine‑based myeloablative conditioning for children with thalassemia major

Lüftinger, Roswitha; Zubarovskaya, Natalia; Galimard, Jacques‑Emmanuel; Cseh, Annamaria; Salzer, Elisabeth; Locatelli, Franco; Algeri, Mattia; Yeşilipek, Akif; Fuente, Josu de la; Isgro, Antonella; Alseraihy, Amal; Angelucci, Emanuele; Smiers, Frans J.; Nasa, Giorgia La La; Zecca, Marco; Fışgın, Tunç; Ünal, Emel; Kleinschmidt, Katharina; Peters, Christina; Lankester, Arjan; Çorbacıoğlu, Selim (Annals of Hematology, 2021)

Signifcant advances in supportive care for patients with transfusion-dependent thalassemia major (TDT) have improved patients’ life expectancy. However, transfusion-associated iron overload remains a signifcant barrier ...

Could the COVID-19 infection have a better prognosis than expected in pediatric hematology oncology and bone marrow transplant patients?

Öner, Özlem Başoğlu; Aksoy, Barış Adaklı; Sütçü, Murat; Çipe, Funda; Atça, Ali Önder; Bozkurt, Ceyhun; Fışgın, Tunç (Scientific Letter, 2021)

Coronavirus disease 2019 (COVID-19) is a pandemic that spread rapidly worldwide (1). So far, very few reports concerning the impact of COVID-19 among patients with pediatric hematologic-oncologic diseases are available ...

Unexpected debris after post thawing donor stem cells in autologous transplantation

Aksoy, Başak Adaklı; Fışgın, Tunç (Elsevier Editora Ltda, 2021)

High dose chemotherapy followed by autologous stem cell transplantation is still a salvage therapy for those patients having relapsed Wilms’ tumor. The most common stem cell source is peripheral blood especially after ...

COVID-19 infection in children with cancer and stem cell transplant recipients in Turkey: A nationwide study

Kebudi, Rejin; Kurucu, Nilgün; Tuğcu, Deniz; Hacısalihoğlu, Sadan; Fışgın, Tunç; Ocak, Süheyla; Kara, Ateş; Bozkurt, Ceyhun (Wiley, 2021)

Adults with cancer are reported to have a higher risk for coronavirus disease (COVID-19) infection and more severe disease and mortality than the general population.1,2 Although children seem to be at a lower risk for ...

Comparison of hematopoietic stem cell transplantation results in patients with beta-thalassemia major from three different graft types

Aydoğdu, Selime; Toret, Ersin; Aksoy, Başak A.; Aydın, Muhammed Fatih; Cipe, Funda E.; Bozkurt, Ceyhun; Fışgın, Tunç (Taylor & Francis Ltd, 2021)

Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for beta-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord ...

Prognostic factors for survival in children who relapsed after allogeneic hematopoietic stem cell transplantation for acute leukemia

Hazar, Volkan; Tezcan Karasu, Gülsün; Öztürk, Gülyüz; Küpesiz, Alphan; Aksoylar, Serap; Özbek, Namık; Gökçe, Müge; Fışgın, Tunç (Wiley, 2021)

Background Post-transplant relapse has a dismal prognosis in children with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Data on risk factors, treatment options, and outcomes are ...

Primary immunodeficiencies: HSCT experiences of a single center in Turkey

Cipe, Funda Erol; Aydoğdu, Selime; Dikme, Gürcan; Kıykım, Ayça; Aydoğmuş, Çiğdem; Yücel, Esra; Bozkurt, Ceyhun; Fışgın, Tunç (Pediatric Transplantation, 2021)

Background Primary immunodeficiency diseases (PID) are characterized by the occurrence of frequent infections and are caused by many genetic defects. Hematopoietic stem cell transplantation (HSCT) is the only curative ...

Farklı yaş grubundaki sıçanlarda laparaskopik ve açık cerrahi sonrası hücresel immun yanıt

Öztaş, Tülin; Bıçakçı, Ünal; Rızalar, Rıza; Fışgın, Tunç (2021)

GİRİŞ ve AMAÇ: Bu çalışmanın amacı farklı yaş gruplarındaki sıçanlarda açık ve laparoskopik cerrahi sonrası hücresel immun yanıttaki değişiklikleri karşılaştırmaktır. YÖNTEM ve GEREÇLER: Çalışmada 24 adet Wistar ...