Karadeniz-Yıldırım, AyşeTanyıldızı-Kökkülünk, Handan2025-05-262025-05-262025Karadeniz-Yıldırım, A., Tanyıldızı-Kökkülünk, H. (2025). Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using monte carlo simulations. Physical and Engineering Sciences in Medicine.2662-47372662-4729https://hdl.handle.net/20.500.12939/5755This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy. Materials and methods: A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities. Results: For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs. Conclusion: In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.eninfo:eu-repo/semantics/openAccessABSInternal dosimetryNuclear medicinePLAPhantomArticle10.1007/s13246-025-01532-2400802582-s2.0-105000383281Q2WOS:001443855800001Q3