Browsing by Author "Özalp, V. Cengiz"
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A facile and efficient method of enzyme immobilization on silica particles via Michael acceptor film coatings: immobilized catalase in a plug flow reactor
Bayramoğlu, Gülay; Arıca, M. Yakup; Genç, Ayşenur; Özalp, V. Cengiz; İnce, Ahmet; Bıçak, Niyazi (Springer, 2016)A novel method was developed for facile immobilization of enzymes on silica surfaces. Herein, we describe a single-step strategy for generating of reactive double bonds capable of Michael addition on the surfaces of silica ... -
Adsorption and separation of immunoglobulins by novel affinity core-shell beads decorated with protein L and L-histidine
Bayramoğlu, Gülay; Özalp, V. Cengiz; Arıca, M. Yakup (Elsevier Science Bv, 2013)A novel core shell beaded chromatographic materials was prepared by grafting of glycidyl methacrylate (GMA) on to the surface of poly(hydoxypropyl methacrylate/ethyleneglycol dimethacrylate), p(HPMA/EGDMA) beads via ... -
Antioxidant activity and hemocompatibility study of quercetin loaded plga nanoparticles
Derman, Serap; Uzunoğlu, Deniz; Acar, Tayfun; Arasoğlu, Tulin; Uçak, Samet; Özalp, V. Cengiz; Mansuroğlu, Banu (Shaheed Beheshti Univ, Sch Pharmacy, 2020)Quercetin (QU) is an important flavonoid compound presenting lots of biological activities, but its application has been limited due to its low aqueous solubility and instability. In this study, conducted to improve these ... -
Design of a core-shell type immuno-magnetic separation system and multiplex PCR for rapid detection of pathogens from food samples
Özalp, V. Cengiz; Bayramoğlu, Gülay; Arica, M. Yakup; Oktem, H. Avni (Springer, 2013)We report an immuno-magnetic separation system developed by the immobilization of pathogen-specific antibodies on the core-shell magnetic beads. The magnetic beads were grafted with glycidylmethacrylate (GMA) using ... -
Development of a paper-type tyrosinase biosensor for detection of phenolic compounds
Şenyurt, Özge; Eyidoğan, Füsun; Yılmaz, Remziye; Öz, M. Tufan; Özalp, V. Cengiz; Arıca, Yakup; Öktem, Huseyin A. (Wiley-Blackwell, 2015)A low-cost, portable, and disposable paper-type tyrosinase biosensor was developed for determination of phenolic compounds, using a paper-strip absorption method. Tyrosinase and a chromophore (3-methyl-2-benzothiazolinone ... -
Lysozyme specific aptamer immobilized MCM-41 silicate for single-step purification and quartz crystal microbalance (QCM)-based determination of lysozyme from chicken egg white
Bayramoğlu, Gülay; Özalp, V. Cengiz; Yılmaz, Meltem; Güler, Ulku; Salih, Bekir; Arıca, M. Yakup (Elsevier, 2015)In the present study, MCM-41 silica particles were functionalized with 3-aminopropyltriethoxysilane (APTES) and characterized by FTIR, SEM, TEM and, Brunauer Emmett Teller (BET) analysis. A lysozyme specific aptamer was ... -
Magnetic silica nanoparticle-Taq polymerase hybrids for multiple uses in polymerase chain reaction
Özalp, V. Cengiz; Bayramoğlu, Gülay; Arıca, M. Yakup (Royal Soc Chemistry, 2015)Enzyme-magnetic nanoparticle hybrids have been employed as a strategy to improve the biocatalytic usability of biological molecules. For this purpose, we synthesized magnetic core-silica shell nanoparticles for direct ... -
Removal of disperse red 60 dye from aqueous solution using free and composite fungal biomass of lentinus concinnus
Bayramoğlu, Gülay; Özalp, V. Cengiz; Arıca, M. Yakup (Iwa Publishing, 2017)Lentinus concinnus biomass was immobilized to carboxyl derivative of cellulose, carboxymethyl cellulose (CMC), in the presence of FeCl3 (0.1 mol L-1) via ionic cross-linking. The beads containing immobilized fungal biomass ... -
Small molecule detection by lateral flow strips via aptamer-gated silica nanoprobes
Özalp, V. Cengiz; Cam, Dilek; Hernandez, Frank J.; Hernandez, Luiza I.; Schafer, Thomas; Öktem, Hüseyin A. (Royal Soc Chemistry, 2016)A fast, sensitive and ratiometric biosensor strategy for small molecule detection was developed through nanopore actuation. The new platform engineers together, a highly selective molecular recognition element, aptamers, ...