Browsing by Author "Fışgın, Tunç"
Now showing items 1-20 of 32
-
Are the anxiety levels of pediatric hematology-oncology patients different from healthy peers during the COVID-19 outbreak?
Çakıroğlu, Süleyman; Yeltekin, Ceren; Fışgın, Tunç; Öner, Özlem B.; Aksoy, Başak A.; Bozkurt, Ceyhun (Lippincott Williams and Wilkins, 2020)The COVID-19 outbreak has caused anxiety among children with hematology-oncology disease and their families, as it has in every segment of society. In this study, we aimed to detect the anxiety levels of children with ... -
Biallelic form of a known CD3E mutation in a patient with severe combined immunodeficiency
Erman, Baran; Fırtına, Sinem; Fışgın, Tunç; Bozkurt, Ceyhun; Cipe, Funda Erol (Springer/Plenum Publishers, 2020)To the Editor: T cell receptor (TCR) complex consists of αβ or γδ TCR chains in combination with four CD3 subunits, CD3ε, CD3γ, CD3δ, and CDζ [1]. This complex is required for thymocyte development and the initiation of T ... -
Busulfan–fudarabine‑ or treosulfan–fudarabine‑based myeloablative conditioning for children with thalassemia major
Lüftinger, Roswitha; Zubarovskaya, Natalia; Galimard, Jacques‑Emmanuel; Cseh, Annamaria; Salzer, Elisabeth; Locatelli, Franco; Algeri, Mattia; Yeşilipek, Akif; Fuente, Josu de la; Isgro, Antonella; Alseraihy, Amal; Angelucci, Emanuele; Smiers, Frans J.; Nasa, Giorgia La La; Zecca, Marco; Fışgın, Tunç; Ünal, Emel; Kleinschmidt, Katharina; Peters, Christina; Lankester, Arjan; Çorbacıoğlu, Selim (Annals of Hematology, 2021)Signifcant advances in supportive care for patients with transfusion-dependent thalassemia major (TDT) have improved patients’ life expectancy. However, transfusion-associated iron overload remains a signifcant barrier ... -
Central nervous system fungal infections in children with leukemia and undergoing hematopoietic stem cell transplantation: A retrospective multicenter study
Karaman, Serap; Kebudi, Rejin; Kızılocak, Hande; Karakaş, Zeynep; Demirağ, Bengü; Evim, Melike Sezgin; Yaralı, Neşe; Kaya, Zühre; Karagün, Barbaros Şahin; Aydoğdu, Selime; Çalışkan, Ümran; Ayhan, Aylin Canbolat; Bahadır, Ayşenur; Çakır, Betül; Güner, Burçak T.; Albayrak, Canan; Karapınar, Deniz Yılmaz; Kazancı, Elif Güner; Ünal, Ekrem; Türkkan, Emine; Akıcı, Ferhan; Bor, Özcan; Vural, Sema; Yılmaz, Şebnem; Apak, Hilmi; Baytan, Birol; Tahta, Neryal Müminoğlu; Güzelküçük, Zeliha; Koçak, Ülker; Antmen, Bülent; Tokgöz, Hüseyin; Fışgın, Tunç; Özdemir, Nihal; Güneş, Adalet Meral; Vergin, Canan; Ünüvar, Ayşegül; Özbek, Namık; Tuğcu, Deniz; Bay, Sema Büyükkapu; Tanyıldız, Hikmet Gülşah; Celkan, Tiraje (2022)Background: Central nervous system fungal infections (CNSFI) are seen in patients with hematologic malignancies and have high morbidity and mortality. Because of their rarity, there is limited data on CNSFI in children ... -
Comparison of allogeneic stem cell transplantation results from related or unrelated donors in beta-thalassemia major
Aydoğdu, Selime; Mergen, Azize; Aksoy, Başak; Çokluk, Mila N.; Dikme, Gürcan; Cipe, Funda; Bozkurt, Ceyhun (Nature Publishing Group, 2019)Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for beta-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord ... -
Comparison of hematopoietic stem cell transplantation results in patients with beta-thalassemia major from three different graft types
Aydoğdu, Selime; Toret, Ersin; Aksoy, Başak A.; Aydın, Muhammed Fatih; Cipe, Funda E.; Bozkurt, Ceyhun; Fışgın, Tunç (Taylor & Francis Ltd, 2021)Allogeneic hematopoietic stem cell transplantation (HSCT) is the curative therapy for beta-thalassemias that induces severe life-threatening complications. The human leukocyte antigen (HLA) registries and umbilical cord ... -
Comparison of turkish stem cell coordination center (TURKOK) with Istanbul University bone marrow bank (TRIS); a single center experience in match unrelated donors
Mergen, Azize; Aydoğdu, Selime; Aksoy, Başak; Savcı, Yunus Emre; Dikme, Gürcan; Cipe, Funda; Fışgın, Tunç (Nature Publishing Group, 2019)[No abstract available] -
Could the COVID-19 infection have a better prognosis than expected in pediatric hematology oncology and bone marrow transplant patients?
Öner, Özlem Başoğlu; Aksoy, Barış Adaklı; Sütçü, Murat; Çipe, Funda; Atça, Ali Önder; Bozkurt, Ceyhun; Fışgın, Tunç (Scientific Letter, 2021)Coronavirus disease 2019 (COVID-19) is a pandemic that spread rapidly worldwide (1). So far, very few reports concerning the impact of COVID-19 among patients with pediatric hematologic-oncologic diseases are available ... -
COVID-19 disease in children and adolescents following allogeneic hematopoietic stem cell transplantation: A report from the Turkish pediatric bone marrow transplantation study group
Bozkurt, Ceyhun; Hazar, Volkan; Malbora, Barış; Küpesiz, Alphan; Aygüneş, Utku; Fışgın, Tunç; Karakükçü, Musa; Kuşkonmaz, Barış; Kılıç, Suar Çakı; Bayırlı, Derya; Bilir, Özlem Arman; Yalçın, Koray; Gözmen, Salih; Uygun, Vedat; Elli, Murat; Sarbay, Hakan; Küpesiz, Funda Tayfun; Şaşmaz, Hatice İlgen; Aksoy, Başak Adaklı; Yılmaz, Ebru; Okur, Fatma Visal; Tekkeşin, Funda; Yenigürbüz, Fatma Demir; Özek, Gülcihan; Atay, Abdullah Avni; Bozkaya, İkbal Ok; Çelen, Suna; Öztürkmen, Seda; Güneş, Adalet Meral; Gürsel, Orhan; Güler, Elif; Özcan, Alper; Çetinkaya, Duygu Uçkan; Aydoğdu, Selime; Özbek, Namık Yaşar; Karasu, Gülsün; Sezgin, Gülay; Doğru, Ömer; Albayrak, Davut; Öztürk, Gülyüz; Aksoylar, Serap; Daloğlu, Hayriye; Al, Işık Odaman; Evim, Melike Sezgin; Akbayram, Sinan; Öncül, Yurday; Zengin, Emine; Albayrak, Canan; Timur, Çetin; Kar, Yeter Düzenli; Çakmaklı, Hasan Fatih; Tüfekçi, Özlem; Töret, Ersin; Antmen, Bülent (2024)Background: Data on the risk factors and outcomes for pediatric patients with SARS-CoV-2 infection (COVID-19) following hematopoietic stem cell transplantation (HSCT) are limited. Objectives: The study aimed to analyze ... -
COVID-19 infection in children with cancer and stem cell transplant recipients in Turkey: A nationwide study
Kebudi, Rejin; Kurucu, Nilgün; Tuğcu, Deniz; Hacısalihoğlu, Sadan; Fışgın, Tunç; Ocak, Süheyla; Kara, Ateş; Bozkurt, Ceyhun; Ince, Dilek; Aras, Seda; Aycicek, Ali; Aksoy, Basak Adakli; Karadas, Nihal; Ozturk, Gulyuz; Orhan, Mehmet Fatih; Ataseven, Eda; Akbayram, Sinan; Yilmaz, Ebru; Tufekci, Ozlem; Vural, Sema; Akyay, Arzu; Ayhan, Aylin Canbolat; Kilic, Suar; Uzel, Veysiye Hulya; Duzenli, Yeter; Acipayam, Can; Elli, Murat; Tanyeli, Atilla; Karakas, Zeynep; Somer, Ayper; Kara, Ates (Wiley, 2021)Adults with cancer are reported to have a higher risk for coronavirus disease (COVID-19) infection and more severe disease and mortality than the general population.1,2 Although children seem to be at a lower risk for ... -
Donor lymphocyte infusion administrations after allogeneic stem cell transplantations in pediatrics: A single center experience
Aydoğdu, Selime; Mergen, Azize; Aksoy, Başak; Akbay, Hazal S.; Cipe, Funda; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)Allogeneic stem cell transplantation (allo-SCT) is considered the cornerstone in the treatment of several malignant and not malignant hematological diseases. However, relapse of hematological disease after allo-SCT is ... -
The effect of biofilm inhibitor N-acetylcysteine on the minimum inhibitory concentration of antibiotics used in Gram-negative bacteria in the biofilm developed on catheters
The study determined the effect of N-acetylcysteine (NAC) on the susceptibility of various antibiotics used to treat Gram-negative catheter-related infection in isolates obtained from pediatric patients admitted to the ... -
Epidemiologic and microbiologic evaluation of catheter-line bloodstream infection in a pediatric hematopoietic stem cell transplant center
Adaklı Aksoy, Başak; Kara, Manolya; Sütçü, Murat; Özbek, Ahmet; Zengin Ersoy, Gizem; Başoğlu Öner, Özlem; Aydoğdu, Selime; Gül, Doruk; Bozkurt, Ceyhun; Fışgın, Tunç (2023)Background: Children who underwent hematopoietic stem cell transplant (HSCT) are at high risk of developing central-line-associated bloodstream infection (CLABSIs). The present study aimed to identify possible risk factors ... -
Evaluation of the risk factors for BK virus-associated hemorrhagic cystitis in pediatric bone marrow transplantation patients: Does post-transplantation cyclophosphamide increase the frequency?
Ersoy, Gizem Zengin; Bozkurt, Ceyhun; Aksoy, Başak Adaklı; Öner, Özlem Başoğlu; Aydoğdu, Selime; Çipe, Funda; Sütçü, Murat; Özkaya, Ozan; Fışgın, Tunç (2022)Background: BKV-HC is one of the most significant complications of HSCT. This ret -rospective study aimed to determine the frequency of BKV-HC in pediatric patients undergoing HSCT, detect the ... -
Extracorporeal photopheresis treatment for steroid resistant graft versus host disease in pediatrics: Single center experience
Aksoy, Başak Adaklı; Savcı, Yunus Emre; Mergen, Azize; Aydoğdu, Selime; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç (Nature Publishing Group, 2019)[No abstract available] -
Farklı yaş grubundaki sıçanlarda laparaskopik ve açık cerrahi sonrası hücresel immun yanıt
Öztaş, Tülin; Bıçakçı, Ünal; Rızalar, Rıza; Fışgın, Tunç (2021)GİRİŞ ve AMAÇ: Bu çalışmanın amacı farklı yaş gruplarındaki sıçanlarda açık ve laparoskopik cerrahi sonrası hücresel immun yanıttaki değişiklikleri karşılaştırmaktır. YÖNTEM ve GEREÇLER: Çalışmada 24 adet Wistar ... -
Immune reconstitution of thalassemia major patients after 1 year of hematopoetic stem cell transplantation
Cipe, Funda Erol; Bozkurt, Ceyhun; Aksoy, Başak Adaklı; Aydoğdu, Selime; Dikme, Gürcan; Fışgın, Tunç (Nature Publishing Group, 2019)Immune reconstitution inflammatory syndrome (IRIS) is a clinical condition emerging after immune recovery of an immunocompromised status, mostly in human immunodeficiency virus infected patients but also in several other ... -
The impact of Treosulfan-based conditioning for inborn errors of immunity: Is dose monitoring crucial?
Ersoy, Gizem Zengin; Çipe, Funda; Fışgın, Tunç; Adaklı Aksoy, Başak; Başoğlu Öner, Özlem; Hashemi, Nazlı; Aydoğdu, Selime; Erdem, Melek; Dikme, Gürcan; Murat, Koza; Bozkurt, Ceyhun (2023)Introduction: In children with inborn errors of immunity (IEI) who will receive a hematopoietic stem cell transplant (HSCT) treosulfan-based conditioning is currently preferred. The aim of this study was to investigate ... -
The inhibitory effects of amylase and streptokinase on minimum inhibitory concentration of antibiotics used to treat gram negative bacteria biofilm infection on indwelling devices
The study evaluated and compared the effect of adding streptokinase and amylase to antibiotics that are already used in clinical practice to treat Gram negative bacteria biofilm infection on indwelling devices on the ...
