Browsing by Author "Kavruk, Murat"
Now showing items 1-9 of 9
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Antibiotic loaded nanocapsules functionalized with aptamer gates for targeted destruction of pathogens
Kavruk, Murat; Çelikbıçak, Ömer; Özalp, Veli Cengiz; Borsa, Barış Ata; Hernandez, Frank J.; Bayramoğlu, Gülay; Arıca, Yakup (Royal Soc Chemistry, 2015)In this study, we designed aptamer-gated nanocapsules for the specific targeting of cargo to bacteria with controlled release of antibiotics based on aptamer-receptor interactions. Aptamer-gates caused a specific decrease ... -
Aptamers in medical diagnosis
Özalp, Veli Cengiz; Kavruk, Murat; Dilek, Özlem; Bayraç, Abdullah Tahir (Pan Stanford Publishing Pte. Ltd., 2016)Aptamers have been increasingly applied in biomedical field as a class of biorecognition elements that possess many advantages such as high specificity and binding affinity, easy synthesis, easy modification, small size, ... -
Aptamers: Molecular tools for medical diagnosis
Özalp, Veli Cengiz; Kavruk, Murat; Dilek, Özlem; Bayraç, Abdullah Tahir (Bentham Science Publ Ltd, 2015)Aptamers have been increasingly applied in biomedical field as a class of biorecognition elements that possess many advantages such as high specificity and binding affinity, easy synthesis, easy modification, small size, ... -
Label-free lateral flow assay for Listeria monocytogenes by aptamer-gated release of signal molecules
Taşbaşı, B. Büşra; Güner, Buket C.; Sudağıdan, Mert; Uçak, Samet; Kavruk, Murat; Özalp, Veli Cengiz (Academic Press Inc Elsevier Science, 2019)Lateral flow assay (LFA) type of biosensors have been popular due to cost-effectiveness and easy-interpretation for instant results, most common examples of applications being pregnancy tests, food safety or medical ... -
Nanocapsules in biomedicine promises and challenges
Hernandez, Frank J.; Kavruk, Murat; Hernandez, Luiza I.; Özalp, Veli Cengiz (Scrivener Publishing Llc, 2015)With the recent advances in nanotechnology, in the past decade, the ways of doing biomedicine have been reshaped considerably. Nanometer-size structures (nanoparticles, nanowires, nanocapsules, etc.) are used in biosensing, ... -
NanoKeepers: Stimuli responsive nanocapsules for programmed specific targeting and drug delivery
Hernandez, Frank J.; Hernandez, Luiza I.; Kavruk, Murat; Arıca, Yakup M.; Bayramoğlu, Gülay; Borsa, Barış Ata; Özalp, Veli Cengiz (Royal Soc Chemistry, 2014)Bacterial resistance is a high priority clinical issue worldwide. Thus, an effective system that rapidly provides specific treatment for bacterial infections using controlled dose release remains an unmet clinical need. ... -
Nanoparticle embedded enzymes for improved lateral flow sensors
Özalp, Veli Cengiz; Zeydanlı, Uğur S.; Lunding, Anita; Kavruk, Murat; Öz, M. Tufan; Eyidoğan, Füsun; Öktem, Huseyin A. (Royal Soc Chemistry, 2013)In this study, combining the nanoparticle embedded sensors with lateral flow assays, a novel strategy for ensuring the quality of signalling in lateral flow assays (LFAs) was developed. A LFA for reactive oxygen species ... -
Pathogen detection by core-shell type aptamer-magnetic preconcentration coupled to real-time PCR
Özalp, Veli Cengiz; Bayramoğlu, Gülay; Kavruk, Murat; Keskin, Batuhan B.; Öktem, Hüseyin A.; Arıca, M. Yakup (Academic Press Inc Elsevier Science, 2014)The presence of pathogenic bacteria is a major health risk factor in food samples and the commercial food supply chain is susceptible to bacterial contamination. Thus, rapid and sensitive identification methods are in ... -
Portable bioactive paper-based sensor for quantification of pesticides
Kavruk, Murat; Özalp, Veli Cengiz; Öktem, Hüseyin Avni (Hindawi Ltd, 2013)A paper-based biosensor was developed for the detection of the degradation products of organophosphorus pesticides. The biosensor quantifies acetylcholine esterase inhibitors in a fast, disposable, cheap, and accurate ...
