Browsing by Author "Schaefer, Thomas"
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DNA Aptamers are functional molecular recognition sensors in protic Ionic liquids
Machado, Isabel; Özalp, Veli Cengiz; Rezabal, Elixabete; Schaefer, Thomas (Wiley-V C H Verlag Gmbh, 2014)The function and structural changes of an AMP molecular aptamer beacon and its molecular recognition capacity for its target, adenosine monophosphate (AMP), was systematically explored in solution with a protic ionic liquid, ... -
DNA-aptamer gating membranes
Schaefer, Thomas; Özalp, Veli Cengiz (Royal Soc Chemistry, 2015)This report describes a membrane barrier whose permeability is modulated through the recognition of a small-molecule target, adenosine triphosphate (ATP), by a DNA-aptamer. The gating function of the DNA-aptamer in the ... -
In situ monitoring of DNA-aptavalve gating function on mesoporous silica nanoparticles
Özalp, Veli Cengiz; Pinto, Alessandro; Nikulina, Elizaveta; Chuvilin, Andrey; Schaefer, Thomas (Wiley-V C H Verlag Gmbh, 2014)Mesoporous silica nanoparticles have proved to be efficient stimuli-responsive controlled release systems for drug delivery when functionalized with nanovalves. Nucleic acid aptamers have recently been adapted to function ...