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    Donor lymphocyte infusion administrations after allogeneic stem cell transplantations in pediatrics: A single center experience
    (Nature Publishing Group, 2019) Aydoğdu, Selime; Mergen, Azize; Aksoy, Başak; Akbay, Hazal S.; Cipe, Funda; Dikme, Gürcan; Bozkurt, Ceyhun; Fışgın, Tunç
    Allogeneic stem cell transplantation (allo-SCT) is considered the cornerstone in the treatment of several malignant and not malignant hematological diseases. However, relapse of hematological disease after allo-SCT is considered the most challenging point in the field. The risk can be reduced through optimal patients, donor and disease selection before allo-SCT, but harnessing donor immune system is an appealing way to treat or avoid disease relapse. Donor lymphocyte infusion (DLI) is a simple and effective therapy after allo-SCT. In this paper, the efficacy of DLI will be analyzed in different hematological diseases, focusing also on their therapeutic or pre-emptive use.