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Öğe Embryo quality assessment in in vitro fertilization (IVF) using metabolite footprints secreted to human embryo culture media by ATR-FTIR spectroscopy and multivariate analysis(Oxford Univ Press, 2016) Garip, S.; Ceyhan, S. T.; Korkmaz, C.; Müge, A.; Güney, E.; Bal, E.; Severcan, FerideObjective of this study is the embryo quality can be determined noninvasively using FTIR spectroscopy to analyze human embryo culture media in IVF treatment. In this prospective, double-blind study, embryo quality was determined by analyzing spent culture media after fertilization by ATR-FTIR spectroscopy and hierarchical cluster analysis (HCA). For each patient, transferred embryos were selected according to morphological assessment and ATR-FTIR studies were carried out collaterally without knowing the morphological grading of each embryo.
