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Recurrence of langerhans cell histiocytosis of jaws: a case report with one year follow-up
(Altınbaş Üniversitesi, 2019) Okumuş, Özlem; Olgaç, Vakur; Özbayrak, Semih
Langerhans cell histiocytosis (LCH) is an unusual disorder characterized by high proliferation of Langerhans cells. A 27-year-old male patient was referred to the Oral Medicine Clinic, Faculty of Dentistry, Altınbaş University with a complaint of wound that does not heal for eight months. The clinical examination showed palatal mucosal ulceration extending to the bone at the upper right first molar region and ulceration at the lingual mucosa of the lower right first molar. The patient had been previously evaluated by a different dentist and was told that it was an aphthous lesion. A punch biopsy from the palatal mucosa and alveolar mucosa near the lesion revealed Langerhans cells and positive reaction to CD1 so the patient was diagnosed with LCH. The insignificant treatment trials may lead to diagnostic delay. Oral lesions may be the earliest symptom of LCH and in most cases; the oral cavity may be the only area involved. Awareness of lesions in the oral mucosa is important in achieving the accurate and early diagnosis and effective treatment plan.