Composition and acetylcholinesterase inhibition properties of tripleurospermum inodorum (L.) Sch. Bip. essential oil from Istanbul
| dc.authorid | 0000-0002-6595-6850 | en_US |
| dc.authorid | 0000-0001-5493-2995 | en_US |
| dc.contributor.author | Servi, Hüseyin | |
| dc.contributor.author | Yüce, Yasemin Yücel | |
| dc.contributor.author | Polatoğlu, Kaan | |
| dc.date.accessioned | 2021-06-11T07:53:06Z | |
| dc.date.available | 2021-06-11T07:53:06Z | |
| dc.date.issued | 2018 | en_US |
| dc.department | Fakülteler, Eczacılık Fakültesi | en_US |
| dc.description.abstract | Essential oil composition and Acetylcholinesterase (AChE) inhibition properties of Tripleurospermum inodorum (L.) Sch. Bip. were investigated. Essential oils of flowers, leaves and stems were obtained through hydro-distillation using a Clevenger type apparatus with 0.03, 0.02 and 0.01% (v/w) yields, respectively. Essential oil composition of the oils was determined by GC-MS analyses. Total of ninety compounds were identified in flower oil comprising of 80.7% of the essential oil. The main components of the flower oil were artemisia ketone 14.4%, terpinen-4-ol 5.5%, 1,8-cineole 5.1%, sabinene 4.7% and tricosane 4.6%. Leaf oil was characterized by 35 compounds representing 62.7% of the oil. Leaf oil contained caryophyllene oxide 16.0%, phytol 12.1%, spathulenol 5.9%, hexahydrofarnesyl acetone 3.8% and salvia-4(14)-en-1-one 3.5% compounds with high relative percentages. Stem essential oil comprised of twenty-eight compounds representing 87.2% of the oil. The main components of the stem essential oil were were neryl acetate 12.8%, (E)-β-farnesene 12.5%, phytol 12.1%, guaia-6,10(14)-dien-4β-ol 10.8%, γ-cadinol 7.8%, nonacosane 7.3%, decanoic acid 6.3% and caryophyllene oxide 4.6%. In vitro AchE inhition of the oils were evaluated by the Ellman spectrophotometric method. AChE inhibitory property was investigated for the flower oil with at four different concentrations. Highest AChE inhibitory property was observed for 20 mg/mL oil concentration (53.35 ± 1.37 %; n =3). This AChE inhibitory concentration was equivalent to the activity of 1.26 μg galanthamine hydrobromide in the assay. Activity of the essential oil was concentration dependent. | en_US |
| dc.identifier.citation | Servi, H., Yücel, Y. Y., & Polatoğlu, K. (2018). Composition and acetylcholinesterase inhibition properties of tripleurospermum inodorum (L.) Sch. Bip. essential oil from Istanbul. Aurum Journal of Health Sciences, 1(1), 23-38. | en_US |
| dc.identifier.endpage | 38 | en_US |
| dc.identifier.issn | 2651-2815 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 23 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12939/2011 | |
| dc.identifier.volume | 1 | en_US |
| dc.institutionauthor | Servi, Hüseyin | |
| dc.institutionauthor | Polatoğlu, Kaan | |
| dc.institutionauthor | Yücel, Yasemin Yücel | |
| dc.language.iso | en | |
| dc.publisher | Altınbaş Üniversitesi | en_US |
| dc.relation.ispartof | AURUM Journal Health Sciences | |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Tripleurospermum Inodorum | en_US |
| dc.subject | Essential Oils | en_US |
| dc.subject | AChE Inhibition | en_US |
| dc.subject | Artemisia Ketone | en_US |
| dc.subject | Caryophyllene Oxide | en_US |
| dc.subject | Neryl Acetate | en_US |
| dc.title | Composition and acetylcholinesterase inhibition properties of tripleurospermum inodorum (L.) Sch. Bip. essential oil from Istanbul | |
| dc.type | Article |
