BCG vaccine and new tuberculosis vaccines against mycobacterium tuberculosis: A review
Yükleniyor...
Dosyalar
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Altınbaş Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Mycobacterium tuberculosis (M. tuberculosis) causes tuberculosis (TB) which is a serious infectious disease. Bacteria are spread from person to person through tiny droplets released into the air via sneezing and coughing. Despite global efforts to control TB, the disease is the second most common cause of death after Acquired Immune Deficiency Syndrome (AIDS). Currently, Bacillus Calmette-Guérin (BCG) vaccine is used to prevent tuberculous meningitis and miliary disease, particularly in young children, but its protective efficacy is variable in adults. Therefore, there is an urgent need for the development of alternative TB vaccines. Recently, new TB vaccine development efforts have been advanced in different clinical studies. Most of these vaccines are live-attenuated or recombinant mycobacterium, live viral vector-based, and protein/adjuvant vaccines. This review explains the recapitulation of the current status of new TB vaccines updated with scientific literature references.
Açıklama
Anahtar Kelimeler
Mycobacterium Tuberculosis, New Vaccines, Clinical Studies, BCG, Rewies
Kaynak
AURUM Journal Health Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
2
Sayı
2
Künye
Kısa, Ö. (2020). BCG Vaccine and new tuberculosis vaccines against mycobacterium tuberculosis: A review. Aurum Journal of Health Sciences, 2(2), 141-153.
