2022 - Cilt 4 - Sayı 2
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Öğe Determination of radiation exposure of students during their internships using OSL dosimeter(Altınbaş Üniversitesi, 2022) Kökkülünk, Handan Tanyıldızı; Aydın, İrfan; Yıldırım, ÖzlemTo keep the radiation exposure under control is the golden rule for radiation protection. The internal structure of the human body could be visible thanks to radiology and nuclear medicine for the aim of diagnosis, and it was possible to destroy tumor cells with external radiation thanks to radiation oncology for the aim of therapy. Radiation dose monitoring is performed for radiation workers however no dose follow-up has for students. So, in this study it was aimed to determine the level of radiation exposure of students who trained in medical imaging techniques program. This work is assessed the radiation exposure of 132 students during their internships in the department of radiology, nuclear medicine and oncology with the aid of optically stimulated luminescence (OSL) dosimeters between the years of 2019-2017. The OSL dosimeters were sent to the RADKOR Personnel Dosimeter Systems Laboratory (Ankara, Turkey) for measurement. Exposed OSL dosimeters were read according to the laboratory specific method based on IEC 62387. Equivalent doses are defined as for body Hp(10) and skin Hp(0,07). Also Hp(10) and Hp(0,07) are defined in the body of each person considered, their values vary from one person to another and also depend on the location on the body where the dosemeter is worn. For the students in the roles of trainers, maximum accumulated equivalent doses were found to be 2.07 and 2.14 mSv for body Hp(10) and skin Hp(0.07), respectively. The minimum accumulated equivalent dose was 0.00 mSv for 112 students both body and skin. The mean Hp(10) and Hp(0,07) for the 1st, 2nd, 3rd and 4th periods were calculated as 0.23±0.38mSv and 0.20±0.35mSv, 0.27±0.42mSv and 0.23±0.34mSv, 0.18±0.37mSv and 0.12±0.30mSv, 0.22±0.63mSv and 0.04±0.34mSv, respectively. The results were evaluated with reference to the Radiation Safety Regulation reported by IAEA. According to the regulation, the effective dose for radiation officers cannot exceed 20 mSv for the whole five consecutive years, and 50 mSv for any year. The annual equivalent dose limit for hand and foot or skin is 500 mSv and 150 mSv for the eyepiece. Therefore, it was determined that all absorbed doses found under the radiation safety regulations. However, it was seen that some students whose absorbed dose were found a little bit high acted more courageous with the self-confidence.Öğe A descriptive study to determine the relationship between health literacy level and catching covid-19(Altınbaş Üniversitesi, 2022) Özkoç, Özgül; Çayırtepe Kılıç, Zuhal; Oktay, İnciThe purpose of this study is to determine whether there is a relationship between Health Literacy level and catching Covid 19 and whether there is a relationship between catching Covid-19 and sociodemographic characteristics. The Quantitative research method was used in this study. Surveys were collected from people aged 18 and over. with a convenience sampling method. The scale’s internal consistency was measured with Cronbach’s alpha test, the correlation between the overall scale and its subdimensions was analyzed with Pearson’s Correlation Coefficient. The relationship between health literacy level and catching Covid-19; and demographic characteristics and catching Covid-19 were measured with a chi-square test. We found a statistically significant relationship between catching Covid-19 and general health literacy level and its two subdimensions (prevention of disease, health promotion). We couldn’t find a statistically significant relationship between healthcare Health Literacy level and catching Covid-19. In addition, there are statistically significant differences in four sociodemographic groups (sex, age, education, marital status) in seeing Covid-19. Public health policymakers may prevent the spread of infectious and pandemic diseases by increasing the health literacy level of citizens. Decision-makers may prioritize their studies according to sociodemographic differences, especially older and low-educated people.Öğe Nano formulations as drug delivery systems(Altınbaş Üniversitesi, 2022) Yılmaz Kayan, Sema; Komesli, YeldaClassical drug forms are used frequently and in repeated doses. Undesirable situations may occur when the dose used for the concentration of the active substance released into the system falls below the sufficient amount or rises above the toxic level. As a result of the developments achieved in nanotechnological research, nanoparticles, which have many applications in the clinic, have made a significant impact in the pharmaceutical industry. The practical use of nanoparticles in applications such as direct binding to the active substance, entrapment and targeting in the pharmaceutical industry has made nanoparticles a preferred position. When implanted systems with nanocarriers reach the target area, uptake in organs, tissues and cells increases. These structures use active and passive targeting strategies to deliver the active substance to the targeted cells. The use of nanocarriers in drug delivery systems provides many advantages. The results obtained from the studies carried out so far are that, thanks to the targeting of cancer drug-loaded nanocarriers, treatment alternatives with higher selectivity have emerged. In this study, nanoparticles as drug delivery are discussed and how to increase bioavailability with nanoparticles is discussed with their advantages.Öğe Diagnosis and treatment methods of autoimmune myasthenia gravis : a systematic review(Altınbaş Üniversitesi, 2022) Yangın, Melike Nur; Zorlu, Yaşar; Severcan, FerideMyasthenia Gravis (MG), which is an autoimmune disorder, causes abnormalities in the neuromuscular junction and has a prevalence of 15-20 per 100,000 people. Although skeletal and extraocular muscles are commonly affected by the disease, approximately 10% of patients have severe involvement in the muscles necessary for respiration. A myasthenic crisis may cause life-threatening consequences. The prevalence and incidence of autoimmune MG increase with age. Women’s disease incidence peaks between the ages of 30 and 40, while men’s incidence peaks between the ages of 60 and 80. The existence of autoantibodies against postsynaptic membrane proteins is the most crucial indicator of MG. Anti-AChR (acetylcholine receptor antibody) positive is a distinct feature of MG (% 80). While antiMuSK (muscle-specific kinase antibody) positivity is detected in 1-10% of all patients, LRP4 (low density lipoprotein receptor related protein 4) antibody positivity is seen in 3-25% of MG patients without AChR and MuSK antibodies (anti-LRP4). Despite many methods used in the diagnosis of MG, it is not possible to make the diagnosis in some patients because of conditions that may vary from patient to patient, such as fluctuation in symptoms and clinical findings. Rapid diagnosis is crucial in patients with MG, because effective treatment must begin as early as possible to prevent potentially fatal complications. Moreover, rapid diagnosis of patients and determination of the patient’s subtype is an important step in the treatment process. Therefore, the aim of this study is to summarize the techniques used in the diagnosis and treatment of MG which is one of the rare diseases.
