A novel marker for esophageal cancer: Senescence marker protein-30

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dc.contributor.authorKızıltan, Remzi
dc.contributor.authorAydın, Mehmet Akif
dc.contributor.authorAlgül, Şermin
dc.contributor.authorKemik, Özgür
dc.date.accessioned2024-02-24T07:50:59Z
dc.date.available2024-02-24T07:50:59Z
dc.date.issued2024en_US
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü,Genel Cerrahi Ana Bilim Dalıen_US
dc.description.abstractAim: Esophageal cancer is one of the most common malignancies causing the majority of cancer -related deaths worldwide. The aim of this study was to examine the importance of preoperative Senescence marker protein -30 (SMP30) levels in patients with esophageal cancer. Material and Methods: Medical records of 85 patients who were diagnosed with esophageal cancer were reviewed and compared with those of the control subjects. The tumor marker was measured with Enzyme -linked immunosorbent assay (ELISA). Results: No statistically significant difference was found between the patient and study groups in terms of age and gender. In our study, we found that serum SMP30 levels were significantly lower in esophageal cancer patients than in healthy controls. Discussion: We found that the adhesion of esophageal cancer cells was significantly reflected by preoperative serum levels of the studied marker, indicating the adhesive strength of cancer cells. SMP30 may be a novel strategy for clinical diagnosis of the disease.en_US
dc.identifier.citationKızıltan, R., Aydın, M. A., Algül, Ş., Kemik, Ö. (2024). A novel marker for esophageal cancer: Senescence marker protein-30. Annals of Clinical and Analytical Medicine, 15(2), 99-102. 10.4328/ACAM.21810en_US
dc.identifier.endpage102en_US
dc.identifier.issn2667-663X
dc.identifier.issue2en_US
dc.identifier.startpage99en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12939/4625
dc.identifier.volume15en_US
dc.identifier.wosWOS:001157822900013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAydın, Mehmet Akif
dc.language.isoen
dc.relation.ispartofAnnals of Clinical and Analytical Medicine
dc.relation.isversionof10.4328/ACAM.21810en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSenescence Marker Protein-30en_US
dc.subjectSMP30en_US
dc.subjectEsophageal Canceren_US
dc.titleA novel marker for esophageal cancer: Senescence marker protein-30
dc.typeArticle

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