Effects of serum biochemical parameters on the prevalence of colon polyps

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dc.contributor.authorAydin, Muhammet Fatih
dc.date.accessioned2025-02-06T17:58:19Z
dc.date.available2025-02-06T17:58:19Z
dc.date.issued2021
dc.departmentAltınbaş Üniversitesien_US
dc.description.abstractAim: Early detection of colorectal polyps is important to prevent malignant transformation. The levels of several metallic and hematologic parameters may be indicators of these polyps. The objective of this study was to investigate whether iron levels may indicate the presence of colorectal polyps. Material and Methods: A total of 897 patients who underwent routine biochemical analysis and colonoscopy were retrospectively evaluated. Patients were grouped as polyp (-) and polyp (+) and further divided into two groups as those with neoplastic polyps and the patients with non-neoplastic polyps. The levels of iron, ferritin, hemoglobin, glucose, cholesterol, triglycerides and vitamin D were compared between the groups. Results: Males accounted for 60.5% of all patients, and 39.5% were females. The mean age of the patients was found as 43.3 +/- 11.9 years. The mean iron (p=0.023), ferritin (p=0.002), cholesterol (p=0.008) and triglycerides (p=0.005) levels were significantly higher in patients with polyps compared to those without polyps. The mean iron (p=0.001), ferritin (p<0.001), hemoglobin (p<0.001) and triglyceride (p=0.007) levels were higher in the males compared to the females. The mean iron (p<0.001), ferritin (p<0.001) and cholesterol (p=0.020) levels were significantly higher in patients with neoplastic polyps compared to those with non-neoplastic polyps. Discussion: Iron levels were elevated in individuals with colorectal polyps and further elevated in patients with neoplastic polyps. Determination of cut-off values of iron and other parameters in predicting colorectal polyps will enable early detection of colorectal polyps and proper intervention.en_US
dc.identifier.doi10.4328/ACAM.20521
dc.identifier.endpage779en_US
dc.identifier.issn2667-663X
dc.identifier.issue7en_US
dc.identifier.startpage775en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20521
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5173
dc.identifier.volume12en_US
dc.identifier.wosWOS:000732429500014
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAydin, Muhammet Fatih
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250206
dc.subjectColorectal polypsen_US
dc.subjectNeoplasticen_US
dc.subjectNon-neoplasticen_US
dc.subjectIronen_US
dc.subjectFerritinen_US
dc.subjectHemoglobinen_US
dc.titleEffects of serum biochemical parameters on the prevalence of colon polypsen_US
dc.typeArticleen_US

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