Clinical and microbiological evaluation of the efficacy of herbal mouthwashes in gingivitis
Yükleniyor...
Dosyalar
Tarih
2025
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Altınbaş Üniversitesi, Lisansüstü Eğitim Enstitüsü
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVE: This randomize controlled clinical trial (RCT) aims to clinically and
microbiologically evaluate the effectiveness of different herbal mouthwashes as an adjunct
treatment to non-surgical periodontal therapy (NSPT) in patients with gingivitis.
MATERIALS AND METHODS: A total of 52 patients diagnosed with gingivitis were
incorporated into the RCT and categorized into four groups as follows: Tea tree oil
(Tebodont®), thyme hydrosol (Arifoglu®), essential oil (Listerine®), and placebo. The
patients were advised to wash with15 ml of prescribed mouthwash twice a day for a
period of 3
rd months after NSPT. Clinical periodontal measurements; including plaque
index (PI), gingival index (GI) and probing pocket depth (PPD) and microbiological
sampling, were performed before enrollment and in 3
rd months. Plaque samples were
examined by quantitative polymerase chain reaction (qPCR).
RESULTS: All four groups had significant reductions in PI, GI, and PPD levels from
beginning to the third month (p<0.05). Intergroup comparisons demonstrated a
significantly higher reduction in PPD in the essential oil and thyme hydrosol groups
compared to the control group (p<0.05). The PI reduction was significantly higher in the
tea tree oil group when comparing with the essential oil group at the third month (p<0.05). The essential oil group exhibited the least drop in GI scores. The levels of P.
gingivalis significantly decreased in all groups (p<0.05).
CONCLUSION: It has been demonstrated that, with regular use, herbal mouth rinses are
effective and may serve as an however, studies with a positive control group, larger study
population and longer period are needed to further evaluate the efficacy of herbal
mouthwashes. Also, in-vitro studies to clarify the mechanism of anti-bacterial action of
herbal mouthwashes are needed.
Açıklama
Anahtar Kelimeler
Gingivitis, Essential Oil, Tea Tree Oil, Thyme, qPCR
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Güneş, C. P. (2025). Clinical and microbiological evaluation of the efficacy of herbal mouthwashes in gingivitis. (Yayınlanmamış doktora tezi). Altınbaş Üniversitesi, Lisansüstü Eğitim Enstitüsü, İstanbul.
