Clinical and microbiological evaluation of the efficacy of herbal mouthwashes in gingivitis
| dc.contributor.author | Güneş, Candan Pelin | |
| dc.date.accessioned | 2025-05-22T08:22:51Z | |
| dc.date.available | 2025-05-22T08:22:51Z | |
| dc.date.issued | 2025 | |
| dc.department | Enstitüler, Lisansüstü Eğitim Enstitüsü, Periodontoloji Ana Bilim Dalı | |
| dc.description.abstract | OBJECTIVE: This randomize controlled clinical trial (RCT) aims to clinically and microbiologically evaluate the effectiveness of different herbal mouthwashes as an adjunct treatment to non-surgical periodontal therapy (NSPT) in patients with gingivitis. MATERIALS AND METHODS: A total of 52 patients diagnosed with gingivitis were incorporated into the RCT and categorized into four groups as follows: Tea tree oil (Tebodont®), thyme hydrosol (Arifoglu®), essential oil (Listerine®), and placebo. The patients were advised to wash with15 ml of prescribed mouthwash twice a day for a period of 3 rd months after NSPT. Clinical periodontal measurements; including plaque index (PI), gingival index (GI) and probing pocket depth (PPD) and microbiological sampling, were performed before enrollment and in 3 rd months. Plaque samples were examined by quantitative polymerase chain reaction (qPCR). RESULTS: All four groups had significant reductions in PI, GI, and PPD levels from beginning to the third month (p<0.05). Intergroup comparisons demonstrated a significantly higher reduction in PPD in the essential oil and thyme hydrosol groups compared to the control group (p<0.05). The PI reduction was significantly higher in the tea tree oil group when comparing with the essential oil group at the third month (p<0.05). The essential oil group exhibited the least drop in GI scores. The levels of P. gingivalis significantly decreased in all groups (p<0.05). CONCLUSION: It has been demonstrated that, with regular use, herbal mouth rinses are effective and may serve as an however, studies with a positive control group, larger study population and longer period are needed to further evaluate the efficacy of herbal mouthwashes. Also, in-vitro studies to clarify the mechanism of anti-bacterial action of herbal mouthwashes are needed. | |
| dc.identifier.citation | Güneş, C. P. (2025). Clinical and microbiological evaluation of the efficacy of herbal mouthwashes in gingivitis. (Yayınlanmamış doktora tezi). Altınbaş Üniversitesi, Lisansüstü Eğitim Enstitüsü, İstanbul. | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12939/5751 | |
| dc.identifier.yoktezid | 928230 | |
| dc.institutionauthor | Güneş, Candan Pelin | |
| dc.language.iso | en | |
| dc.publisher | Altınbaş Üniversitesi, Lisansüstü Eğitim Enstitüsü | |
| dc.relation.publicationcategory | Tez | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Gingivitis | |
| dc.subject | Essential Oil | |
| dc.subject | Tea Tree Oil | |
| dc.subject | Thyme | |
| dc.subject | qPCR | |
| dc.title | Clinical and microbiological evaluation of the efficacy of herbal mouthwashes in gingivitis | |
| dc.type | Doctoral Thesis |
