A comparative analysis of biofilm characteristics of Dual-Species periodontopathogenic biofilm based on fusobacterium nucleatum and the Dual-Species biofilm response in the presence of antimicrobial peptide
dc.authorid | 0000-0002-4929-800X | en_US |
dc.contributor.author | Keskin, Mutlu | |
dc.date.accessioned | 2021-06-11T08:53:23Z | |
dc.date.available | 2021-06-11T08:53:23Z | |
dc.date.issued | 2020 | en_US |
dc.department | Meslek Yüksekokulları, Sağlık Hizmetleri Meslek Yüksekokulu, Ağız ve Diş Sağlığı Programı | en_US |
dc.description.abstract | Fusobacterium nucleatum (F.nucleatum), which acts as a linking periodontopathogenic bacteria, has the ability of coaggregation with early and late colonization species. It is the most intense gram-negative bacteria found in periodontal health and increases in periodontal diseased areas numerically. In this study, comparative analyses of dual and mono-biofilm structural characteristics formed by Porphyromonas gingivalis and Prevotella intermedia with F. nucleatum have been evaluated. In all results, more biofilm formation was observed in dual-species compared to monospecies biofilms. Biofilm formation of F. nucleatum-P.intermedia has increased in the presence of Human Neutrophilic Peptide (HNP-1). In this study it is concluded that dual-periodontopathogenic coaggregations based on F. nucleatum could produce more intense biofilm structure than single-species ones, and the increase in dual-species biofilm mass in the presence of low doses of HNP-1 may be a defense mechanism of dual periodontopathogenic biofilm. | en_US |
dc.identifier.citation | Keskin, M. (2020). A comparative analysis of biofilm characteristics of Dual-Species periodontopathogenic biofilm based on fusobacterium nucleatum and the Dual-Species biofilm response in the presence of antimicrobial peptide. Aurum Journal of Health Sciences, 2(1), 1-10. | en_US |
dc.identifier.endpage | 10 | en_US |
dc.identifier.issn | 2651-2815 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 1 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12939/2055 | |
dc.identifier.volume | 2 | en_US |
dc.institutionauthor | Keskin, Mutlu | |
dc.language.iso | en | |
dc.publisher | Altınbaş Üniversitesi | en_US |
dc.relation.ispartof | AURUM Journal Health Sciences | |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Periodontitis | en_US |
dc.subject | Subgingival | en_US |
dc.subject | Biofilm | en_US |
dc.subject | Antimicrobial | en_US |
dc.subject | Peptide | en_US |
dc.title | A comparative analysis of biofilm characteristics of Dual-Species periodontopathogenic biofilm based on fusobacterium nucleatum and the Dual-Species biofilm response in the presence of antimicrobial peptide | |
dc.type | Article |