Effects of the pathological characteristics on the presence of multicentric thyroid tumors in the contralateral lobe

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dc.contributor.authorPamukcu, Muhammet
dc.contributor.authorDemir, Emine
dc.contributor.authorAydin, Mehmet Akif
dc.date.accessioned2025-02-06T17:58:19Z
dc.date.available2025-02-06T17:58:19Z
dc.date.issued2022
dc.departmentAltınbaş Üniversitesien_US
dc.description.abstractAim: In this study, we aimed to investigate the effects of pathological tumor characteristics on the presence of a multicentric tumor in the contralateral lobe in papillary thyroid carcinoma (PTC). Material and Methods: A total of 46 patients aged over 18 years who underwent total thyroidectomy due to PTC in our clinic were retrospectively evaluated. Patients' demographic data such as age and gender, preoperative USG findings, postoperative pathological findings, lobe localization, and the presence of nodules in the contralateral lobe were recorded. In addition, tumor size, presence of nuclear atypia, mitotic activity, vascular invasion and extrathyroidal spread of the tumor and the presence of lymph node metastasis were obtained from pathological reports. Patients were divided into two groups as multicentric and non-multicentric, and the data were compared between these groups. Results: The mean age of the patients was 44.9 +/- 12.3 years. Twenty-three patients had papillary thyroid microcarcinoma and 23 patients had papillary thyroid carcinoma. Postoperative pathological examination revealed multicentric PTCs in 15 patients . No statistically significant difference was found between patients with and without multicentric contralateral lobe tumors in terms of primary tumor diameter, nuclear atypia, mitotic activity, tumor necrosis, vascular invasion, extrathyroidal spread and lymph node metastasis (for all p>0.05). Discussion: The pathology of the tumor in the contralateral lobe of the primary nodule can be seen with preoperative USG in the majority of patients with PTC. The presence of a multicentric tumor in the contralateral lobe is not correlated with tumor size and pathological characteristics of the tumor.en_US
dc.identifier.doi10.4328/ACAM.20952
dc.identifier.endpage294en_US
dc.identifier.issn2667-663X
dc.identifier.issue3en_US
dc.identifier.startpage291en_US
dc.identifier.urihttps://doi.org/10.4328/ACAM.20952
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5169
dc.identifier.volume13en_US
dc.identifier.wosWOS:000734193900001
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherBayrakol Medical Publisheren_US
dc.relation.ispartofAnnals of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250206
dc.subjectPapillary Thyroid Carcinomaen_US
dc.subjectMicrocarcinomaen_US
dc.subjectMultifocalen_US
dc.subjectMulticentricen_US
dc.subjectTumor Sizeen_US
dc.subjectMetastasisen_US
dc.titleEffects of the pathological characteristics on the presence of multicentric thyroid tumors in the contralateral lobeen_US
dc.typeArticleen_US

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