Relationship between fibrinogen values and sensitivity and specificity of STS ccore, euroscore for patients undergoing open heart surgery

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dc.contributor.authorAydınlı, Bahar
dc.contributor.authorTekin, Esra Ertürk
dc.contributor.authorYeşiltaş, Mehmet Ali
dc.contributor.authorOkşen, Doğaç
dc.contributor.authorÖzmen, Harun
dc.date.accessioned2025-01-03T10:54:44Z
dc.date.available2025-01-03T10:54:44Z
dc.date.issued2024en_US
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractBackground/Aim: Cardiovascular diseases are a leading cause of mortality worldwide, with surgical interventions playing a crucial role in outcomes. Despite technological advancements and improved operator experience, perioperative and postoperative risks remain significant, particularly for high-risk patients. Fibrinogen, an acute-phase reactant, increases during inflammation and plays a role in coagulation. This study investigates the prognostic impact of fibrinogen levels on the outcomes of cardiac surgery and evaluates its relationship with established risk classification systems. Materials and Methods: This observational cohort study included 105 patients who underwent cardiac surgery between May 2018 and December 2023. Patients with coronary bypass grafting and valve surgery were included, while those with transplantation, congenital heart surgery, or other significant conditions were excluded. Patient data, including demographic information, comorbidities, laboratory parameters, and surgical details, were collected. The fibrinogen cutoff value was determined using the Youden index. Statistical analyses were performed using SPSS 23.0, with p-values < 0.05 considered significant. Results: Of the 116 individuals screened, 105 were included in the study. The HighFib group (>3.8 g/dL) showed higher rates of complications, such as low cardiac output, prolonged mechanical ventilation, and atrial fibrillation, compared to the LowFib group (<3.8 g/dL). The HighFib group also had lower preoperative hemoglobin levels and higher Euroscore values. Logistic regression analysis demonstrated that both fibrinogen levels and established risk scores were significant predictors of postoperative complications. Conclusion: Elevated fibrinogen levels are associated with increased postoperative complications in cardiac surgery patients. Fibrinogen, alongside traditional risk scores, can be a valuable predictor of adverse outcomes. Prospective studies are needed to further validate these findings and establish optimal fibrinogen management strategies in cardiac surgery.en_US
dc.identifier.citationAydınlı, B., Tekin, E. E., Yeşiltaş, M. A., Oksen, D., Özmen, H. (2024). Relationship between fibrinogen values and sensitivity and specificity of STS ccore, euroscore for patients undergoing open heart surgery. Heart Surgery Forum, 27(12), E1397-E1403. 10.59958/hsf.8011en_US
dc.identifier.endpageE1403en_US
dc.identifier.issn1098-3511
dc.identifier.issue12en_US
dc.identifier.scopus2-s2.0-85212538332
dc.identifier.scopusqualityQ3
dc.identifier.startpageE1397en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5137
dc.identifier.volume27en_US
dc.identifier.wosWOS:001394466300005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorOkşen, Doğaç
dc.language.isoen
dc.publisherForum Multimedia Publishing LLCen_US
dc.relation.ispartofHeart Surgery Forum
dc.relation.isversionof10.59958/hsf.8011en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiac surgeryen_US
dc.subjectComplicationsen_US
dc.subjectFibrinogenen_US
dc.subjectPostoperativEen_US
dc.subjectPrognosisen_US
dc.subjectRisk assessmenten_US
dc.titleRelationship between fibrinogen values and sensitivity and specificity of STS ccore, euroscore for patients undergoing open heart surgery
dc.typeArticle

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