Investigation of the Biological Activities of Alcea calvertii

Basit Öğe Kaydı
dc.authoridAbudayyak, Mahmoud/0000-0003-2286-4777
dc.contributor.authorAbudayyak, Mahmoud
dc.contributor.authorKanbolat, Seyda
dc.contributor.authorErgene, Reyyan
dc.contributor.authorBatur, Seyma
dc.contributor.authorAliyazicioglu, Rezzan
dc.date.accessioned2025-02-06T17:58:20Z
dc.date.available2025-02-06T17:58:20Z
dc.date.issued2022
dc.departmentAltınbaş Üniversitesien_US
dc.description.abstractHerbs are widely used in the treatment of diseases as colds, infections, and cancer. In this work, we evaluate Alcea calvertii, which is a perennial herbaceous plant belonging to the Malvaceae family. It spreads in Anatolia and Mediterranean region and has important uses in terms of ethnobotany. In this study, it was aimed to evaluate the cytotoxic potentials and to investigate the antioxidant activities of methanol, water, chloroform, and ethyl acetate extracts of the aerial parts of Alcea calvertii. For that, the antioxidant activity of Alcea calvertii was determined by four antioxidant power (FRAP), copper reducing antioxidant capacity (CUPRAC) and 2,2-diphenylpicrylhydrazil (DPPH) radical scavenging activity. The cytotoxicity potential of extracts was assessed in the human lung cancer cell line (A549) by MTT assay. It was observed that the highest antioxidant activity was in the methanol extract and the antioxidant activity increased with increasing extract concentration; The TPC values were between 62.5 - 414.6 GAE mu g mL-1, the FRAP values were between 115.7 - 1321.4 mu M Trolox equivalent g-1, CUPRAC values were between 177.1 1321.4 mu M Trolox equivalent g-1, and IC50 values in DPPH caused cytotoxicity in a concentration dependent manner, the IC50 developing new drugs.en_US
dc.description.sponsorshipTUEBGTAK; [1919B011800561]en_US
dc.description.sponsorshipThis study was supported by TUEBGTAK 2209A '' University Students Domestic Research Projects Support Program '' project number 1919B011800561.en_US
dc.identifier.doi10.18016/ksutarimdoga.vi.890659
dc.identifier.endpage964en_US
dc.identifier.issn2619-9149
dc.identifier.issue5en_US
dc.identifier.startpage955en_US
dc.identifier.trdizinid1133337
dc.identifier.urihttps://doi.org/10.18016/ksutarimdoga.vi.890659
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1133337
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5183
dc.identifier.volume25en_US
dc.identifier.wosWOS:000869734700003
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherKahramanmaras Sutcu Imam Univ Rektorluguen_US
dc.relation.ispartofKsu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Natureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250206
dc.subjectAlcea calvertiien_US
dc.subjectAntioxidant activityen_US
dc.subjectCytotoxicityen_US
dc.titleInvestigation of the Biological Activities of Alcea calvertiien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu