Effects of Caffeic Acid on Human Health: Pharmacological and Therapeutic Effects, Biological Activity and Toxicity

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dc.contributor.authorYazar, Memet
dc.contributor.authorSevindik, Mustafa
dc.contributor.authorUysal, Imran
dc.contributor.authorPolat, Abdullah Ozan
dc.date.accessioned2025-08-14T17:47:05Z
dc.date.available2025-08-14T17:47:05Z
dc.date.issued2025
dc.departmentFakülteler, Tıp Fakültesi
dc.description.abstractPhenolic compounds are bioactive compounds found in many natural products. Natural products exhibit biological activities because of their bioactive compounds. This review presents an overview of the general characteristics of caffeic acid, including its derivatives and biosynthesis, pharmacological and therapeutic effects, and biological activities. According to the literature research conducted, it has been reported that there are medical and pharmacological effects such as atherosclerotic, cardioprotective, immunomodulatory, hypertension, radiotherapy, neurodegeneration, neuroprotective, anxiety, vasoactive, dyslipidemia, and obesity. Furthermore, it has been observed that the substance possesses biological activities such as antioxidant, antihyperglycemic, antimicrobial, anticancer, cytotoxic, anti-inflammatory, anticoagulatory, antidiabetic, and antiviral properties. Within this scope, it is believed that caffeic acid could serve as a significant natural resource in pharmacological designs.
dc.identifier.citationYazar, M., Sevindik, M., Uysal, I., & Polat, A. O. (2025). Effects of Caffeic Acid on Human Health: Pharmacological and Therapeutic Effects, Biological Activity and Toxicity. Pharmaceutical Chemistry Journal, 59(1), 49-55. 10.1007/s11094-025-03363-7
dc.identifier.doi10.1007/s11094-025-03363-7
dc.identifier.endpage55
dc.identifier.issn0091-150X
dc.identifier.issn1573-9031
dc.identifier.issue1
dc.identifier.scopus2-s2.0-105005546948
dc.identifier.scopusqualityQ4
dc.identifier.startpage49
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5921
dc.identifier.volume59
dc.identifier.wosWOS:001491340900001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.institutionauthorYazar, Memet
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofPharmaceutical Chemistry Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectbiological activity
dc.subjectcaffeic acid
dc.subjectpharmacology
dc.subjectphenolic compounds
dc.titleEffects of Caffeic Acid on Human Health: Pharmacological and Therapeutic Effects, Biological Activity and Toxicity
dc.typeArticle

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