Integrative machine learning approaches for enhanced cardiovascular disease prediction: a comparative analysis of XGBoost and ANFIS algorithms

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Tarih

2025

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, highlighting the urgent need for advanced diagnostic tools to improve early detection and patient outcomes. This study evaluates the predictive performance of two machine learning models-Extreme Gradient Boosting (XGBoost) and the Adaptive Neuro-Fuzzy Inference System (ANFIS)-across five datasets from the UCI Machine Learning Repository: Cleveland, Hungary, Switzerland, Long Beach VA, and Statlog Heart. Comprehensive preprocessing steps-including imputation, standardization, one-hot encoding, and SMOTEENN-were applied to ensure data consistency and address class imbalance. XGBoost achieved perfect accuracy (100%) on the Switzerland and Statlog datasets, reflecting its strength in structured data environments and consistent predictive performance. Conversely, ANFIS outperformed XGBoost on the Cleveland dataset, demonstrating its effectiveness in modeling complex, nonlinear relationships. Performance evaluation metrics included accuracy, precision, recall, F1 score, F2 score, and ROC-AUC. XGBoost consistently delivered high precision and recall, which are essential for minimizing false positives and negatives in clinical settings. ANFIS yielded high F2 scores, indicating a stronger emphasis on reducing false negatives-a critical concern in CVD diagnosis. This comparative analysis suggests that while XGBoost is well suited for scalable, high-throughput diagnostic applications, ANFIS offers greater interpretability and is more effective in nuanced clinical scenarios. These findings underscore the potential of integrating advanced machine learning models into cardiovascular disease prediction frameworks to enhance diagnostic accuracy and support real-world healthcare decision-making.

Açıklama

Anahtar Kelimeler

ANFIS, Cardiovascular diseases, Diagnostic predictive modeling, Machine learning, XGBoost

Kaynak

Journal of Supercomputing

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

81

Sayı

12

Künye

Muhyi, D. F., & Ata, O. (2025). Integrative machine learning approaches for enhanced cardiovascular disease prediction: a comparative analysis of XGBoost and ANFIS algorithms. The Journal of Supercomputing, 81(12), 1-48. 10.1007/s11227-025-07687-9