DETERMINATION OF BIOLOGICAL ACTIVITIES OF MICROMERIA MYRTIFOLIA BOISS. & HOHEN

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dc.contributor.authorYücel, Yasemin Yücel
dc.contributor.authorÖzdemi̇R Nath, Ebru
dc.date.accessioned2025-02-06T18:01:18Z
dc.date.available2025-02-06T18:01:18Z
dc.date.issued2024
dc.departmentAltınbaş Üniversitesien_US
dc.description.abstractObjective: Lamiaceae family has a wide variety of well-known and lesser-known plants with strong medicinal qualities. The genus Micromeria Benth. is a member of this family consisting of herbaceous plants with a variety of significant biological, phytochemical, and ethnobotanical uses. In this study, the biological activities of methanol and ethanol extracts of Micromeria myrtifolia were evaluated. Material and Method: To demonstrate the antioxidant activity DPPH radical scavenging activity and total phenolic content assays were done. The effects of the extracts on acetylcholinesterase (AChE) and monoamine oxidase-A were then assessed. Result and Discussion: Methanol extract showed the highest DPPH scavenging activity, at the dose of 10 mg/ml with a value of 96.55%. For the highest concentration that can be applicable, AChE inhibitions for the methanol and ethanol extracts were 25% and 27%, respectively. On the other hand, the inhibitory effects of the ethanol and methanol extracts of the plant on MAO-A were determined; for the ethanol extract IC50 value was found as 32.5876 ± 0.89 μg/ml, and for the methanol extract it was found as 34.6544 ± 0.76 μg/ml. It can be told that M. myrtifolia can act as a potential antioxidant. With further research and investigation, it is thought that Micromeria myrtifolia could be used as a natural source for the treatment of various neurological diseases. © 2024 University of Ankara. All rights reserved.en_US
dc.description.sponsorshipAltınbaş University Scientific Research Fund, (PB2020-ECZ-3)en_US
dc.identifier.doi10.33483/jfpau.1372535
dc.identifier.endpage411en_US
dc.identifier.issn2564-6524
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85196098176
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage406en_US
dc.identifier.trdizinid1236415
dc.identifier.urihttps://doi.org/10.33483/jfpau.1372535
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1236415
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5301
dc.identifier.volume48en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherUniversity of Ankaraen_US
dc.relation.ispartofAnkara Universitesi Eczacilik Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_Scopus_20250206
dc.subjectAcetylcholinesteraseen_US
dc.subjectantioxidant activityen_US
dc.subjectMicromeria myrtifoliaen_US
dc.subjectmonoamine oxidase-Aen_US
dc.subjectneurodegenerative diseasesen_US
dc.titleDETERMINATION OF BIOLOGICAL ACTIVITIES OF MICROMERIA MYRTIFOLIA BOISS. & HOHENen_US
dc.title.alternativeMICROMERIA MYRTIFOLIA BOISS. & HOHEN’İN BİYOLOJİK AKTİVİTELERİNİN BELİRLENMESİen_US
dc.typeArticleen_US

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