Frozen embryo transfer prevents the detrimental effect of high estrogen on endometrium receptivity

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dc.contributor.authorErşahin, Aynur Adeviye
dc.contributor.authorAcet, Mustafa
dc.contributor.authorErşahin, Suat Süphan
dc.contributor.authorGüngör, Nur Dokuzeylül
dc.date.accessioned2021-05-15T12:56:33Z
dc.date.available2021-05-15T12:56:33Z
dc.date.issued2017
dc.departmentTıp Fakültesien_US
dc.description.abstractObjective: To investigate whether serum levels of estradiol affect reproductive outcomes of normoresponder women undergoing fresh embryo transfer (ET) versus frozen-thawed ET (FET).Material and Methods: Two hundred fifty-five normoresponder women underwent fresh ET in their first or second in vitro fertilization cycle. Ninety-two women with negative pregnacy test results underwent FET. Clinical and ongoing pregnancy rates, implantation, and live birth rates of women undergoing fresh ET versus FET were compared. Results: One hundred forty-seven (57.65%) out of the 255 normoresponder women receiving FET had positive beta-human chorionic gonadotrophin (hCG) results. The remaining 108 women had negative beta-hCG results. The clinical pregnancy rates of the fresh ET group were found as 55.69% (n=142). Ninety-two of the 108 women with failed pregnancies underwent FET; 72.83% had positive beta-hCG results (n=67), and 70.65% had clinical pregnancy (n=65). Both biochemical and clinical pregnancy rates of women undergoing FET increased significantly (p<0.012 and p<0.013, respectively). Ongoing pregnancy (60.87% vs. 52.94%) and live birth rates (59.87% vs. 48.63%) were similar in both fresh and FET groups. Serum E2 levels of women who failed to conceive were significantly higher than those women did conceive. Serum progesterone levels of women who conceived versus those that did not were similar. Conclusion: The detrimental effect of high serum estradiol levels on endometrial receptivity could be prevented by FET. (J Turk Ger Gynecol Assoc 2017; 18: 38-42)en_US
dc.identifier.doi10.4274/jtgga.2016.0186
dc.identifier.endpage42en_US
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85016001976
dc.identifier.scopusqualityQ3
dc.identifier.startpage38en_US
dc.identifier.trdizinid287366
dc.identifier.urihttps://doi.org/10.4274/jtgga.2016.0186
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpnM016WTJOZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12939/1484
dc.identifier.volume18en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorErşahin, Suat Süphan
dc.language.isoen
dc.relation.ispartofJournal of the Turkish-German Gynecological Association
dc.relation.publicationcategoryAraştırma Makalesien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectKadın Hastalıkları ve Doğumen_US
dc.titleFrozen embryo transfer prevents the detrimental effect of high estrogen on endometrium receptivity
dc.typeOther

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