Nuclease activity as a specific biomarker for breast cancer

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dc.contributor.authorHernandez, Luiza I.
dc.contributor.authorCengiz Özalp, Veli
dc.contributor.authorHernandez, Frank J.
dc.date.accessioned2021-05-15T12:37:24Z
dc.date.available2021-05-15T12:37:24Z
dc.date.issued2016
dc.departmentTıp Fakültesien_US
dc.descriptionHernandez, Frank J./0000-0001-6308-8087; Ozalp, Veli Cengiz/0000-0002-7659-5990
dc.description.abstractWe report on the activity of nucleases derived from cancer cells as a means for specific targeting using nucleic acid probes (substrates). We hypothesize that cancer cells can be differentiated from healthy cells based on their nuclease activity profile, and thus, any method based on this property represents a novel alternative for diagnostic and therapeutic intervention.en_US
dc.description.sponsorshipDepartment of Innovation (Diputacion de Gipuzkoa)en_US
dc.description.sponsorshipThe authors (LIH and FJH) acknowledge BIC Gipuzkoa (Donostia-San Sebastian, Spain) for hosting them in the "Bioincubator''. Financial support was received from the Department of Innovation (Diputacion de Gipuzkoa).en_US
dc.identifier.doi10.1039/c6cc07108b
dc.identifier.endpage12349en_US
dc.identifier.issn1359-7345
dc.identifier.issn1364-548X
dc.identifier.issue83en_US
dc.identifier.pmid27722495
dc.identifier.scopus2-s2.0-84991492538
dc.identifier.scopusqualityQ1
dc.identifier.startpage12346en_US
dc.identifier.urihttps://doi.org/10.1039/c6cc07108b
dc.identifier.urihttps://hdl.handle.net/20.500.12939/530
dc.identifier.volume52en_US
dc.identifier.wosWOS:000385166800019
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorCengiz Özalp, Veli
dc.language.isoen
dc.publisherRoyal Soc Chemistryen_US
dc.relation.ispartofChemical Communications
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMedicineen_US
dc.subjectBreast Canceren_US
dc.subjectNuclease Activityen_US
dc.titleNuclease activity as a specific biomarker for breast cancer
dc.typeArticle

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