Applications of stem cell-derived extracellular vesicles in nerve regeneration
Yükleniyor...
Dosyalar
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopaedic surgery cases. This review explores the involvement of EVs in nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-free therapies. It underscores the importance of bioengineers comprehending and manipulating EV activity to optimize the efficacy of tissue engineering and regenerative therapies.
Açıklama
Anahtar Kelimeler
Nerve regeneration, Non-coding RNAs, Exosome, Traumatic brain injury, Blood-brain barrier
Kaynak
International Journal of Molecular Sciences
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
25
Sayı
11
Künye
Yavuz, B., Mutlu, E. C., Ahmed, Z., Ben-Nissan, B., Stamboulis, A. (2024). Applications of stem cell-derived extracellular vesicles in nerve regeneration. International Journal of Molecular Sciences, 25(11). 10.3390/ijms25115863
