A COMPARISON OF THE EFFICACY OF DIFFERENT REMINERALIZATION AGENTS: AN IN VITRO STUDY

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Tarih

2025

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Purpose: The objective of this study was to evaluate and compare the remineralizing efficacy of a solution containing silver diamine fluoride (SDF) with agents containing sodium fluoride (NaF) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on artificial caries lesions using laser fluorescence (DIAGNODent) and micro-computed tomography (-CT). Methods: Artificial caries lesions were created on extracted primary incisors without any lesions or defects in the enamel tissue. The teeth were randomly divided into four groups (n = 8): Group 1: SDF (Advantage Arrest, Elevate Oral Care, USA); Group 2: NaF (Clinpro, 3M ESPE, USA); Group 3: CPP-ACP (GC Tooth Mousse, Recaldent, USA); Group 4: control. After applying remineralization agents, the samples were kept in an artificial saliva solution and measured by DIAGNODent at regular intervals. When the remineralization process was complete, enamel surfaces were analyzed by-CT for mineral density, lesion depth, and area using the computer program. Data obtained were statistically analyzed. Results: In the comparison of DIAGNODent values between the groups, a statistically significant difference was found between the values measured on the fourteenth day (p-value=0.003). A significant difference was found between the mineral density (g/cm3) values measured by-CT on the fourteenth day after remineralization according to the groups (p-value=0.001). Conclusions: All agents used in this study provided remineralization. The DIAGNODent and-CT measurements demonstrated that the SDF group had a higher remineralization value than the other groups. Considering the ease of use as well as its effectiveness, it is thought that the SDF solution can be used successfully to arrest early childhood caries. SDF application positively influences enamel remineralization.

Açıklama

Anahtar Kelimeler

DIAGNODent, initial caries, micro-computed tomography, remineralization, silver diamine fluoride

Kaynak

International Society for Fluoride Research

WoS Q Değeri

Q4

Scopus Q Değeri

Cilt

58

Sayı

1

Künye

Düzgün, S. Ö., Görürgöz, C., Ocak, M., Seymen, F., & Koruyucu, M. (2025). A COMPARISON OF THE EFFICACY OF DIFFERENT REMINERALIZATION AGENTS: AN IN VITRO STUDY. Fluoride, 58(1).