A COMPARISON OF THE EFFICACY OF DIFFERENT REMINERALIZATION AGENTS: AN IN VITRO STUDY

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dc.contributor.authorDüzgün, Seçil Özkurt
dc.contributor.authorGörürgöz, Cansu
dc.contributor.authorOcak, Mert
dc.contributor.authorSeymen, Figen
dc.contributor.authorKoruyucu, Mine
dc.date.accessioned2025-05-12T13:29:44Z
dc.date.available2025-05-12T13:29:44Z
dc.date.issued2025
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Çocuk Diş Hekimliği Ana Bilim Dalı
dc.description.abstractPurpose: The objective of this study was to evaluate and compare the remineralizing efficacy of a solution containing silver diamine fluoride (SDF) with agents containing sodium fluoride (NaF) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on artificial caries lesions using laser fluorescence (DIAGNODent) and micro-computed tomography (-CT). Methods: Artificial caries lesions were created on extracted primary incisors without any lesions or defects in the enamel tissue. The teeth were randomly divided into four groups (n = 8): Group 1: SDF (Advantage Arrest, Elevate Oral Care, USA); Group 2: NaF (Clinpro, 3M ESPE, USA); Group 3: CPP-ACP (GC Tooth Mousse, Recaldent, USA); Group 4: control. After applying remineralization agents, the samples were kept in an artificial saliva solution and measured by DIAGNODent at regular intervals. When the remineralization process was complete, enamel surfaces were analyzed by-CT for mineral density, lesion depth, and area using the computer program. Data obtained were statistically analyzed. Results: In the comparison of DIAGNODent values between the groups, a statistically significant difference was found between the values measured on the fourteenth day (p-value=0.003). A significant difference was found between the mineral density (g/cm3) values measured by-CT on the fourteenth day after remineralization according to the groups (p-value=0.001). Conclusions: All agents used in this study provided remineralization. The DIAGNODent and-CT measurements demonstrated that the SDF group had a higher remineralization value than the other groups. Considering the ease of use as well as its effectiveness, it is thought that the SDF solution can be used successfully to arrest early childhood caries. SDF application positively influences enamel remineralization.
dc.identifier.citationDüzgün, S. Ö., Görürgöz, C., Ocak, M., Seymen, F., & Koruyucu, M. (2025). A COMPARISON OF THE EFFICACY OF DIFFERENT REMINERALIZATION AGENTS: AN IN VITRO STUDY. Fluoride, 58(1).
dc.identifier.issn0015-4725
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85218442286
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5743
dc.identifier.volume58
dc.identifier.wosWOS:001428661200005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakScopus
dc.institutionauthorSeymen, Figen
dc.language.isoen
dc.relation.ispartofInternational Society for Fluoride Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDIAGNODent
dc.subjectinitial caries
dc.subjectmicro-computed tomography
dc.subjectremineralization
dc.subjectsilver diamine fluoride
dc.titleA COMPARISON OF THE EFFICACY OF DIFFERENT REMINERALIZATION AGENTS: AN IN VITRO STUDY
dc.typeArticle

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