Current state of lipid nanoparticles (SLN and NLC) for skin applications

Basit Öğe Kaydı
dc.contributor.authorEroğlu, Cemre
dc.contributor.authorSinani, Genada
dc.contributor.authorÜlker, Zeynep
dc.date.accessioned2023-08-21T06:27:46Z
dc.date.available2023-08-21T06:27:46Z
dc.date.issued2023en_US
dc.departmentFakülteler, Eczacılık Teknolojisi Bilimleri Bölümü, Farmasötik Teknoloji Ana Bilim Dalıen_US
dc.description.abstractThe increasing knowledge on skin physiology, formulation science and nanotechnology has led to continuous improvements in cosmetics, and introduction of dermocosmetics has been increasing particularly for the management of skin disorders such as acne, eczema, psoriasis, etc. Nowadays, research has been focused on the development of products which can efficiently administer active compounds to the target skin layers while minimizing side effects. The use of multifunctional lipid nanoparticles for cosmetic and dermocosmetic purposes is promising not only because biocompatible ingredients are used in their composition, but also because of their ability to show enhanced skin penetration. Although the introduction of liposomes has been a hallmark of lipid nanoparticles, development of novel systems capable of encapsulating active compounds with tunable release profiles, that show good stability, are easy to manufacture and handle remains a necessity. Solid lipid nanoparticles (SLN) were introduced as alternative formulations for emulsions, liposomes and polymeric nanoparticles, whereas nanostructured lipid carriers (NLC) were developed later as second-generation nanoparticles. However, both SLN and NLC show many inherited advantageous properties to be used for dermal applications including ability to provide occlusion and photoprotective effect and skin hydration, and various SLN and NLC based products are already in the market. This review provides an overview on the current state-of-art of SLN and NLC particularly for cosmetic and dermocosmetic purposes, discuss their formulation composition, structures and preparation techniques. Their use for the topical delivery of active compounds in different skin disorders is highlighted along with examples of commercialized products.en_US
dc.identifier.citationEroğlu, C., Sinani, G., & Ülker, Z. (2023). Current state of lipid nanoparticles (SLN and NLC) for skin applications. Current Pharmaceutical Design, 29(21), 1632-1644.en_US
dc.identifier.endpage1644en_US
dc.identifier.issn1381-6128
dc.identifier.issn1873-4286
dc.identifier.issue21en_US
dc.identifier.scopus2-s2.0-85169174625
dc.identifier.scopusqualityQ2
dc.identifier.startpage1632en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12939/3681
dc.identifier.volume29en_US
dc.identifier.wosWOS:001062898900002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSinani, Genada
dc.institutionauthorÜlker, Zeynep
dc.language.isoen
dc.relation.ispartofCurrent Pharmaceutical Design
dc.relation.isversionof10.2174/1381612829666230803111120en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCosmeticsen_US
dc.subjectDermocosmeticsen_US
dc.subjectLipid Nanoparticlesen_US
dc.subjectNanostructured Lipid Carriers (NCL)en_US
dc.subjectSkinen_US
dc.subjectSolid Lipid Nanoparticles (SLN)en_US
dc.subjectTopicalen_US
dc.titleCurrent state of lipid nanoparticles (SLN and NLC) for skin applications
dc.typeArticle

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

PubMed İndeksli Yayınlar Koleksiyonu
Eczacılık Fakültesi Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu