Utility of gingival crevicular fluid components for periodontal diagnosis

dc.authorid0000-0001-8830-9835en_US
dc.contributor.authorBuduneli, Nurcan
dc.contributor.authorBıyıkoğlu, Başak
dc.contributor.authorKinane, Denis F.
dc.date.accessioned2024-07-22T08:52:15Z
dc.date.available2024-07-22T08:52:15Z
dc.date.issued2024en_US
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Periodonti Ana Bilim Dalıen_US
dc.description.abstractPeriodontal diseases are highly prevalent chronic diseases, and severe periodontitis creates functional and esthetic problems and decreases self-esteem for a large percentage of the older population worldwide. In many cases of periodontitis, there is no distinct tell-tale pain that motivates a patient to seek treatment, rather the signs become clinically detectable late, and typically when the disease has progressed to a problematic level for the life of the dentition. Early periodontal screening and diagnostics tools will provide early recognition of periodontal diseases and facilitate timely management of the disease to reduce tooth loss. To this goal, gingival crevicular fluid is easily sampled, can be repeatedly and non-invasively collected, and can be tested for potential biomarkers. Moreover, the site specificity of periodontal diseases enhances the usefulness of gingival crevicular fluid sampled from specific sites as a biofluid for diagnosis and longitudinal monitoring of periodontal diseases. The present review aimed to provide up-to-date information on potential diagnostic biomarkers with utility that can be assayed from gingival crevicular fluid samples, focusing on what is new and useful and providing only general historic background textually and in a tabulated format.en_US
dc.identifier.citationBuduneli, N., Bıyıkoğlu, B., Kinane, D. F. (2024). Utility of gingival crevicular fluid components for periodontal diagnosis. Periodontology 2000. 10.1111/prd.12595en_US
dc.identifier.endpage175en_US
dc.identifier.issn0906-6713
dc.identifier.issn1600-0757
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85198331656
dc.identifier.scopusqualityQ1
dc.identifier.startpage156en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12939/4779
dc.identifier.volume95en_US
dc.identifier.wosWOS:001270983000001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBıyıkoğlu, Başak
dc.language.isoen
dc.relation.ispartofPeriodontology 2000
dc.relation.isversionof10.1111/prd.12595en_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiomarkersen_US
dc.subjectDiagnosisen_US
dc.subjectGingival crevicular fluiden_US
dc.subjectPeriodontitisen_US
dc.titleUtility of gingival crevicular fluid components for periodontal diagnosis
dc.typeReview Article

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