Nanocapsules in biomedicine promises and challenges

Basit Öğe Kaydı
dc.contributor.authorHernandez, Frank J.
dc.contributor.authorKavruk, Murat
dc.contributor.authorHernandez, Luiza I.
dc.contributor.authorÖzalp, Veli Cengiz
dc.date.accessioned2021-05-15T12:40:38Z
dc.date.available2021-05-15T12:40:38Z
dc.date.issued2015
dc.departmentTıp Fakültesi, Biyofizik Anabilim Dalıen_US
dc.descriptionKavruk, Murat/0000-0001-5331-7253; Ozalp, Veli Cengiz/0000-0002-7659-5990
dc.description.abstractWith the recent advances in nanotechnology, in the past decade, the ways of doing biomedicine have been reshaped considerably. Nanometer-size structures (nanoparticles, nanowires, nanocapsules, etc.) are used in biosensing, molecular imaging, diagnosis and therapies, based on their exceptionally diverse properties. Properties such as size, morphology, aggregation propensity, functionalization, biocompatibility, and biodegradability are being continuously optimized to maximize their biomedical efficacy. Among these nanostructures, nanocapsules are the next-generation approach promising to control "cellular health," by programming the release of cargo to the target cell or organ based on endogenous (e.g. enzymes and pH) or external (light, magnetic field, ultrasound) stimuli. Nanocapsules are a class of porous polymeric or inorganic particles in the nanometer range, with tunable features such as pore diameter, pore topology, diverse surface properties, and loading efficiencies that can be easily tailored to several biomedical applications. However, the use of nanocapsules in the biomedicine field is still in its infancy. Most studies have been performed in silico or in cell lines, and just very few studies have been done in animal models of disease. This chapter focuses on those studies where nanocapsules have been well characterized in vitro and in vivo, with the potential to be translated into the clinic. Moreover, this chapter also offers an overview of the recent advances in nanocapsule-based approaches for cancer therapy.en_US
dc.identifier.endpage233en_US
dc.identifier.isbn978-1-118-99829-8
dc.identifier.scopus2-s2.0-85019584465
dc.identifier.scopusqualityN/A
dc.identifier.startpage209en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12939/641
dc.identifier.wosWOS:000401545800009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorÖzalp, Veli Cengiz
dc.language.isoen
dc.publisherScrivener Publishing Llcen_US
dc.relation.ispartofAdvanced Theranostics Materials
dc.relation.ispartofseriesAdvanced Materials Series
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiomedicineen_US
dc.subjectNanocapsulesen_US
dc.titleNanocapsules in biomedicine promises and challenges
dc.typeBook Part

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Temel Tıp Bilimleri Bölümü Koleksiyonu