Cognitive impairment in kidney transplanted patients

dc.contributor.authorMalyszko, Jolanta
dc.contributor.authorGolenia, Aleksandra
dc.contributor.authorFarisco, Michele
dc.contributor.authorLo Re, Vincenzina
dc.contributor.authorKlimkowicz-Mrowiec, Aleksandra
dc.contributor.authorCapasso, Giovambattista
dc.contributor.authorGoumenos, Dimitris
dc.contributor.authorRroji, Merita
dc.contributor.authorFigurek, Andreja
dc.contributor.authorHafez, Gaye
dc.contributor.authorCONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators
dc.date.accessioned2025-05-27T05:42:30Z
dc.date.available2025-05-27T05:42:30Z
dc.date.issued2025
dc.departmentFakülteler, Eczacılık Meslek Bilimleri Bölümü, Farmakoloji Ana Bilim Dalı
dc.description.abstractChronic kidney disease affects almost all of the organs. Recently, more attention has been paid to the kidney and the central nervous system connections. In patients on kidney replacement therapy, including kidney transplantation, there is an increased prevalence of cognitive impairment, and depression and other neurological complications, such as cerebrovascular disorders and movement disorders. Kidney transplant recipients need an assessment for the risk factors and the pattern of cognitive impairment (memory, attention and executive function decline). This enables an accurate diagnosis to be made at an earlier stage. Partial post-transplant cognitive impairment recovery is also important. Finally, doctors and patients alike face numerous ethical concerns and challenges regarding the transplantation of kidneys and other solid organs. In this review, we examined some key issues regarding cognitive impairment in kidney transplant patients. We focused on the mechanism of cognitive impairment in kidney transplant recipients, patterns of cognitive impairment; evaluation of patients with cognitive impairment for kidney transplantation, the potential impact of cognitive impairment on waitlisted and transplanted patients on patient care, non-pharmacological interventions and unmet medical needs, psychological and ethical issues in kidney transplantation, and unmet needs. As cognitive impairment in kidney transplant recipients is an underestimated, underrecognized but clinically relevant problem, screening for cognitive function before and after kidney transplantation would be worth considering in standard routine practice.
dc.description.sponsorshipFunding sponsor: European Cooperation in Science and Technology Funding number: CA19127
dc.identifier.citationMalyszko, J., Golenia, A., Farisco, M., Re, V. L., Klimkowicz-Mrowiec, A., Capasso, G., ... & Hafez, G. (2025). Cognitive impairment in kidney transplanted patients. Nephrology Dialysis Transplantation, 40(Supplement_2), ii46-ii53.
dc.identifier.doi10.1093/ndt/gfae250
dc.identifier.endpageii53
dc.identifier.issn0931-0509
dc.identifier.issn1460-2385
dc.identifier.issueSupplement_2
dc.identifier.pmid40080090
dc.identifier.scopus2-s2.0-105000275963
dc.identifier.scopusqualityQ1
dc.identifier.startpageii46
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5756
dc.identifier.volume40
dc.identifier.wosWOS:001443929700003
dc.identifier.wosqualityQ1
dc.indekslendigikaynakPubMed
dc.institutionauthorHafez, Gaye
dc.language.isoen
dc.relation.ispartofNephrology, Dialysis, Transplantation
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectchronic kidney disease
dc.subjectcognitive impairment
dc.subjectethics
dc.subjectkidney transplantation
dc.subjectpsychological issues
dc.titleCognitive impairment in kidney transplanted patients
dc.typeOther

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