Antibiotic loaded nanocapsules functionalized with aptamer gates for targeted destruction of pathogens
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Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Royal Soc Chemistry
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, we designed aptamer-gated nanocapsules for the specific targeting of cargo to bacteria with controlled release of antibiotics based on aptamer-receptor interactions. Aptamer-gates caused a specific decrease in minimum inhibitory concentration (MIC) values of vancomycin for Staphylococcus aureus when mesoporous silica nanoparticles (MSNs) were used for bacteria-targeted delivery.
Açıklama
Ozalp, Veli Cengiz/0000-0002-7659-5990; Kavruk, Murat/0000-0001-5331-7253; Hernandez, Frank J./0000-0001-6308-8087; Celikbicak, Omur/0000-0003-2683-0312
Anahtar Kelimeler
Pathogens
Kaynak
Chemical Communications
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
51
Sayı
40
