The impact of body mass index on the diagnostic and surgical outcomes in primary hyperparathyroidism
Yükleniyor...
Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Associação Médica Brasileira
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVE: The aim of this study was to investigate the influence of body mass index on the diagnostic and surgical outcomes in patients undergoing parathyroidectomy for primary hyperparathyroidism. METHODS: A total of 446 patients with primary hyperparathyroidism were divided into four groups according to their body mass index: normal weight (body mass index<25 kg/m2) (n=130), overweight (25≤body mass index<30 kg/m2) (n=166), obese (30≤body mass index<35 kg/m2) (n=112), and morbidly obese (body mass index≥35 kg/m2) (n=38). Perioperative findings were compared between the groups. RESULTS: The preoperative median parathormone level in the morbidly obese group (204 pg/mL, min:max 72:1,178) was significantly lower than that in the normal-weight (246 pg/mL, min:max 60:4,262) (p=0.026) and obese (251 pg/mL, min:max 74:2,094) (p=0.012) groups. The osteoporosis rate in the normal-weight group (51%) was higher than that in the overweight (35.4%) (p=0.041) and morbidly obese (25%) (p=0.023) groups. The symptomatic hypocalcemia rate in the normal-weight group (10.2%) was significantly higher than that in the obese group (1.8%) (p=0.017). CONCLUSION: Normal-weight patients with primary hyperparathyroidism have higher blood parathormone values, higher rates of osteoporosis, and postoperative symptomatic hypocalcemia compared to patients with higher body mass index. For this reason, the surgeon should consider the possibility of symptomatic hypocalcemia after undergoing parathyroidectomy for primary hyperparathyroidism in normal-weight cases.
Açıklama
Anahtar Kelimeler
Body mass index, Hyperparathyroidism, Obesity, Parathyroidectomy
Kaynak
Revista da Associação Médica Brasileira
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
71
Sayı
3
Künye
Parlak, N. S., Ertekin, S. Ç., & Kırdak, T. (2025). The impact of body mass index on the diagnostic and surgical outcomes in primary hyperparathyroidism. Revista da Associação Médica Brasileira, 71(3), e20240989. 10.1590/1806-9282.20240989
