The impact of body mass index on the diagnostic and surgical outcomes in primary hyperparathyroidism

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dc.authorid0000-0003-2983-1994
dc.authorid0000-0002-2710-4403
dc.authorid0000-0001-6609-4650
dc.contributor.authorParlak, Nazım Serhat
dc.contributor.authorErtekin, Süleyman Çağlar
dc.contributor.authorKırdak, Turkay
dc.date.accessioned2025-08-01T10:06:22Z
dc.date.available2025-08-01T10:06:22Z
dc.date.issued2025
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü,Genel Cerrahi Ana Bilim Dalı
dc.description.abstractOBJECTIVE: The aim of this study was to investigate the influence of body mass index on the diagnostic and surgical outcomes in patients undergoing parathyroidectomy for primary hyperparathyroidism. METHODS: A total of 446 patients with primary hyperparathyroidism were divided into four groups according to their body mass index: normal weight (body mass index<25 kg/m2) (n=130), overweight (25≤body mass index<30 kg/m2) (n=166), obese (30≤body mass index<35 kg/m2) (n=112), and morbidly obese (body mass index≥35 kg/m2) (n=38). Perioperative findings were compared between the groups. RESULTS: The preoperative median parathormone level in the morbidly obese group (204 pg/mL, min:max 72:1,178) was significantly lower than that in the normal-weight (246 pg/mL, min:max 60:4,262) (p=0.026) and obese (251 pg/mL, min:max 74:2,094) (p=0.012) groups. The osteoporosis rate in the normal-weight group (51%) was higher than that in the overweight (35.4%) (p=0.041) and morbidly obese (25%) (p=0.023) groups. The symptomatic hypocalcemia rate in the normal-weight group (10.2%) was significantly higher than that in the obese group (1.8%) (p=0.017). CONCLUSION: Normal-weight patients with primary hyperparathyroidism have higher blood parathormone values, higher rates of osteoporosis, and postoperative symptomatic hypocalcemia compared to patients with higher body mass index. For this reason, the surgeon should consider the possibility of symptomatic hypocalcemia after undergoing parathyroidectomy for primary hyperparathyroidism in normal-weight cases.
dc.identifier.citationParlak, N. S., Ertekin, S. Ç., & Kırdak, T. (2025). The impact of body mass index on the diagnostic and surgical outcomes in primary hyperparathyroidism. Revista da Associação Médica Brasileira, 71(3), e20240989. 10.1590/1806-9282.20240989
dc.identifier.doi10.1590/1806-9282.20240989
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue3
dc.identifier.pmid40332255
dc.identifier.scopus2-s2.0-105004064806
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://hdl.handle.net/20.500.12939/5815
dc.identifier.volume71
dc.identifier.wosWOS:001492174600024
dc.identifier.wosqualityQ2
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorErtekin, Süleyman Çağlar
dc.institutionauthorid0000-0002-2710-4403
dc.language.isoen
dc.publisherAssociação Médica Brasileira
dc.relation.ispartofRevista da Associação Médica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBody mass index
dc.subjectHyperparathyroidism
dc.subjectObesity
dc.subjectParathyroidectomy
dc.titleThe impact of body mass index on the diagnostic and surgical outcomes in primary hyperparathyroidism
dc.typeArticle

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