Small molecule detection by lateral flow strips via aptamer-gated silica nanoprobes
[ X ]
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Royal Soc Chemistry
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A fast, sensitive and ratiometric biosensor strategy for small molecule detection was developed through nanopore actuation. The new platform engineers together, a highly selective molecular recognition element, aptamers, and a novel signal amplification mechanism, gated nanopores. As a proof of concept, aptamer gated silica nanoparticles have been successfully used as a sensing platform for the detection of ATP concentrations at a wide linear range from 100 mu M up to 2 mM.
Açıklama
Ozalp, Veli Cengiz/0000-0002-7659-5990; Hernandez, Frank J./0000-0001-6308-8087
Anahtar Kelimeler
Medicine, Small Molecule Detection, Silica Nanoprobes
Kaynak
Analyst
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
141
Sayı
8
