Small molecule detection by lateral flow strips via aptamer-gated silica nanoprobes

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dc.contributor.authorÖzalp, V. Cengiz
dc.contributor.authorCam, Dilek
dc.contributor.authorHernandez, Frank J.
dc.contributor.authorHernandez, Luiza I.
dc.contributor.authorSchafer, Thomas
dc.contributor.authorÖktem, Hüseyin A.
dc.date.accessioned2021-05-15T12:37:27Z
dc.date.available2021-05-15T12:37:27Z
dc.date.issued2016
dc.departmentTıp Fakültesien_US
dc.descriptionOzalp, Veli Cengiz/0000-0002-7659-5990; Hernandez, Frank J./0000-0001-6308-8087
dc.description.abstractA fast, sensitive and ratiometric biosensor strategy for small molecule detection was developed through nanopore actuation. The new platform engineers together, a highly selective molecular recognition element, aptamers, and a novel signal amplification mechanism, gated nanopores. As a proof of concept, aptamer gated silica nanoparticles have been successfully used as a sensing platform for the detection of ATP concentrations at a wide linear range from 100 mu M up to 2 mM.en_US
dc.identifier.doi10.1039/c6an00273k
dc.identifier.endpage2599en_US
dc.identifier.issn0003-2654
dc.identifier.issn1364-5528
dc.identifier.issue8en_US
dc.identifier.pmid27041474
dc.identifier.scopus2-s2.0-84964751474
dc.identifier.scopusqualityQ1
dc.identifier.startpage2595en_US
dc.identifier.urihttps://doi.org/10.1039/c6an00273k
dc.identifier.urihttps://hdl.handle.net/20.500.12939/538
dc.identifier.volume141en_US
dc.identifier.wosWOS:000374037000038
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzalp, V. Cengiz
dc.language.isoen
dc.publisherRoyal Soc Chemistryen_US
dc.relation.ispartofAnalyst
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMedicineen_US
dc.subjectSmall Molecule Detectionen_US
dc.subjectSilica Nanoprobesen_US
dc.titleSmall molecule detection by lateral flow strips via aptamer-gated silica nanoprobes
dc.typeArticle

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