Combating chronic kidney disease-associated cachexia: A literature review of recent therapeutic approaches
Yükleniyor...
Dosyalar
Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In 2008, the Society on Sarcopenia, Cachexia, and Wasting Disorders introduced a generic definition for all types of cachexia: "a complex metabolic syndrome associated with the underlying illness characterized by a loss of muscle, with or without fat loss". It is well-known that the presence of inflammatory burden in end-stage renal disease (ESRD) patients may lead to the evolution of cachexia. Since the etiology of cachexia in chronic kidney disease (CKD) is multifactorial, thus the successful treatment must involve several concomitant measures (nutritional interventions, appetite stimulants, and anti-inflammatory pharmacologic agents) to provide integrated effective therapeutic modalities to combat causative factors and alleviate the outcomes of patients. Given the high mortality rate associated with cachexia, developing new therapeutic modalities are prerequisite for ameliorating patients with CKD worldwide. The present review aims to discuss some therapeutic strategies and provide an update on advances in nutritional approaches to counteract cachexia.
Açıklama
Anahtar Kelimeler
Cachexia, Chronic kidney disease, End-stage renal disease, Nutrition, Wasting
Kaynak
BMC Nephrology
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
26
Sayı
1
Künye
Rahbar Saadat, Y., Abbasi, A., Hejazian, S. S., Hekmatshoar, Y., Ardalan, M., Farnood, F., & Zununi Vahed, S. (2025). Combating chronic kidney disease-associated cachexia: A literature review of recent therapeutic approaches. BMC nephrology, 26(1), 133.
